[Hemocoagulation disorder and its impact on cerebral hemodynamics in patients with type I diabetes mellitus]. / Narushenie gemokoaguliatsii i ee vliianie na tserebral'nyiu gemodinamiky u bol'nykh sakharnym diabetom I tipa.

Indices were studied for the blood coagulation system in 132 patients with insulin-dependent diabetes mellitus (IDDM). The above indices tended to change toward hypercoagulation. The degree of changes was found to be related to duration and severity of illness. Patients presenting with a grave form DM more than 10 years in duration demobnstrated changes in their coagulograms suggesting the development of the chronic disseminated intravascular coagulation syndrome. Correlation has been established between fibrinogen and indices of reoencephalogram reflecting the state of the cerebral vascular system. The conclusion reached was to the effect that hyperfibrinogenemia makes for reduction in the brain pulse blood, is related to the development of venous discirculation, increase in the rigidity of cerebral vessels and heterogenuity of the blood filling in the brain.

[Disordered cerebral hemodynamics in diabetic patients (based on myelographic data)]. / Narushenie tserebral'noi gemodinamiki u bol'nykh sakharnym diabetom (po dannym mielografii).

Overall seventy-six patients with diabetes mellitus (DM) who ranged from 16 to 65 years old were examined. Of these, 62 subjects were given a diagnosis of insulin-dependent DM, 14 insulin-nondependent DM. Moderate severity course of the illness was documented in 32, severe--in 44 patients. All patients revealed a change in the condition of the cerebrovascular system. This was manifested by predominance of hypertonic type rheograms, increased vasomotor tone with vessels of all calibres, changes in the level of pulse blood filling, signs of varying degree venous hypertension. DM duration, severity, level of compensation were all related to the degree of cerebrovascular disturbances.

[The content of lipid peroxidation products in the blood of patients with disseminated sclerosis]. / Soderzhanie produktov perekisnogo okisleniia lipidov v krovi bol'nykh rasseiannym sklerozom.

Lipid peroxidation products were investigated in patients suffering of multiple sclerosis. Activation of the processes of free-radical oxidation was revealed. Employment of antioxidant therapy in the complex treatment of these patients resulted in an improvement of their condition that correlated with positive changes in the process of lipid peroxidation.