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Rev. esp. patol ; 48(4): 197-202, oct.-dic. 2015. tab, ilus
Artigo em Espanhol | IBECS | ID: ibc-143508

RESUMO

El propósito del estudio fue determinar si en pacientes con cáncer de recto (CR) posterior a tratamiento neoadyuvante (TNA) se puede obtener un adecuado número de ganglios linfáticos (GL) y si este correlaciona con la supervivencia. Setenta pacientes se dividieron en 2 grupos de acuerdo con si recibieron o no TNA. El grupo TNA se dicotomizó en < 12 GL y ≥ 12 GL. Los pacientes del grupo sin TNA mostraron mayor invasión vascular (33,3% vs. 14,3%) y perineural (19% vs. 4,1%). La media de GL del grupo TNA fue 15,7 + 7,1 vs. 27,28 + 14,9 (p = 0,0238) y se disecaron ≥ 12 GL en 74% vs. 90,5% (p = 0,0326). Los subgrupos con <12 y ≥ 12 GL no influyeron en el estadio N, estadio clínico ni supervivencia. La supervivencia media a 5 años del grupo TNA fue 82,3% vs. 76,9% (p = 0,465) (AU)


The aim of this study was to assess the possibility of obtaining an adequate number of lymph nodes (LN) from rectal cancer patients treated with neoadjuvant therapy (NAT) and to evaluate the correlation of LN with survival. 70 patients were divided into two groups: those who had received NAT and those who had not. The NAT group was further divided into those with < 12 LN and > 12 LN. The non-NAT group showed more lymph vascular invasion (33.3% vs. 14.3%) and perineural invasion (19% vs. 4.1%). Average LN in NAT group was 15.7 + 7.1 vs. 27.28 + 14.9 (p = 0.0238) and ≥ 12 LN were resected in 74% vs. 90.5% (p = 0.0326). The <12 and > 12 LN groups showed no difference in N stage, staging and survival. The 5-yr survival of NAT group was 82.3% v 76.9% (p = 0.465) (AU)


Assuntos
Humanos , Masculino , Linfonodos/patologia , Neoplasias Retais/patologia , Neoplasias Retais/tratamento farmacológico , Terapia Neoadjuvante/métodos , Terapia Neoadjuvante , Reto/patologia , Carcinoma/patologia , Sobrevivência
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