RESUMO
The immune system was examined in those who participated in the liquidation of accident sequelae at the Chernobyl Atomic Power Station and the population exposed to ionizing radiation. Alteration in surface antigenic markers of basic regulatory subpopulations of immunocompetent cells and metabolic changes are caused by radiation and co-existent somatic diseases. Typing for HLA antigens and proteins with a genetically determined phenotype revealed characteristic features of their distribution for the general population.
Assuntos
Acidentes , Imunidade/efeitos da radiação , Reatores Nucleares , Antígenos de Grupos Sanguíneos/imunologia , Criança , Enzimas/análise , Antígenos HLA/análise , Humanos , Linfócitos/imunologia , Fenótipo , Radiação Ionizante , Formação de Roseta , UcrâniaRESUMO
The qualitative and quantitative parameters of hemopoiesis and immunocompetent cells were studied in 365 children in the early "iodine" and long-term periods after the accident. In accordance with primary response, a group consisting of 28 subjects with so-called "radiation injury" was distinguished. The early period was marked by unusual qualitative and quantitative hematological changes which, however, did not lead to the development of the hematological syndrome characteristic of acute radiation injury. Certain deviations that corresponded to somatic pathology were detectable at the late periods after the accident.