Role of vitamin B12 in depressive disorder--a case report.

Vitamin B12 deficiency anemia may have psychiatric manifestations preceding the hematological symptoms. Although a variety of symptoms are described, there are only sparse data on the role of vitamin B12 in depression. We report a case of vitamin B12 deficiency presenting with recurrent episodes of depression.

Influence of intracerebroventricularly infused anions on feeding response.

Chloride and bicarbonate solutions of potassium, calcium, sodium, and barium were infused into the third ventricle of the rats to observe the influence of anions on feeding response. Stainless steel cannulae were chronically implanted into the anteroventral part of the third ventricle of 54 rats, which were divided in 9 equal groups. While the control group was given 10 microliters of artificial cerebrospinal fluid intraventricularly, the remaining 8 groups received the equal quantity (10 microliters) of one of the hypertonic equimolar test solutions. Chloride solutions of potassium, calcium, and barium evoked significantly (p less than 0.05) higher feeding than the control group, while none of the bicarbonate solutions influenced feeding significantly. Chloride solutions of all the 4 cations elicited significantly (p less than 0.05) higher feeding than the corresponding bicarbonate solutions in 24 hr. It was observed that though the cations differed, there was no significant difference in the responses elicited by the different chloride solutions. Similarly, various bicarbonate solutions elicited similar responses. Osmolality and pH of the infusion solution have not influenced feeding significantly. It is concluded that the anionic, but not the cationic concentration of the fluid bathing juxtacerebroventricular sensors, predominantly influence the feeding response.

A study of the effects of venous occlusion on haemostatic variables in males and females.

The response of the coagulation-fibrinolysis system to venous occlusion was studied in 20 healthy subjects of both sexes. All of them showed increased fibrinolytic activity, the increase being greater in females. Fibrinogen content also increased in both sexes. The other parameters of coagulation studied showed varied responses.

Effect of exhaustive ergometric exercise on blood coagulation, platelet adhesiveness and fibrinolytic activity in untrained young men and women.

Exhaustive bicycle ergometric exercise in 20 untrained male and female medical students in the age group of 18-25 yrs resulted in significant changes in clotting and prothrombin time, platelet adhesiveness and fibrinolytic activity. Clotting and Prothrombin time were reduced while platelet adhesiveness and fibrinolytic activity were increased in both the sexes.