RESUMO
We report two cases of complex movement disorders induced by fluoxetine. A 72-year-old woman developed rhythmic palatal movements, myoclonus, chorea, and possibly dystonia after 2 years of therapy with fluoxetine. On withdrawal of fluoxetine, the movements abated after 5 days and did not recur. The second patient, a 58-year-old man, developed myoclonic jerking and rapid, stereotypic movements of his toes after a year of fluoxetine therapy. These complex movements have not been reported previously as an adverse effect of fluoxetine.
Assuntos
Antidepressivos de Segunda Geração/efeitos adversos , Transtorno Depressivo/tratamento farmacológico , Discinesia Induzida por Medicamentos/etiologia , Fluoxetina/efeitos adversos , Idoso , Antidepressivos de Segunda Geração/administração & dosagem , Discinesia Induzida por Medicamentos/diagnóstico , Feminino , Fluoxetina/administração & dosagem , Seguimentos , Humanos , Assistência de Longa Duração , Masculino , Pessoa de Meia-Idade , Exame Neurológico/efeitos dos fármacosRESUMO
A case of neuroleptic-induced adult-onset tardive tourettism is presented with video documentation. After prolonged neuroleptic therapy, the patient developed motor and vocal tics at 36 years of age. The tics were identical to those seen in childhood-onset Tourette's syndrome. These cases are rare and have been considered by some to represent tardive akathisia. Previous reports of tourettism after neuroleptic therapy are reviewed.
