RESUMO
A fine motor test involves the manipulation of smaller objects with fingers, hands, and wrists. This test is an integral part of the evaluation of an upper extremity function. Nine Hole Peg Test (NHPT) is one among such tests which assess the ability to manipulate pegs with the thumb and finger. There is a need to develop a fine motor assessment tool which is reproducible and mimics closely the natural movement of hands. The aim of this work is to develop an electronic pegboard which is easy to administer and efficient in terms of time. Pegboard device is modified and standardized by (1) Adding electronic circuits to custom-made pegboard and programmed using a microcontroller (ATmega2560), (2) Following a specific sequence in placing and picking the pegs from the board, and (3) Using Infrared sensor and robust algorithm to ensure one peg movement at a time. The setup is administered on 15 healthy participants (nine females, six males aged between 21 and 80) and the outcome is compared with the results of traditional NHPT. Predefined sequence in moving the pegs and electronic timer features provide reliable results for repeated measurements and facilitate storing test score in a digital repository. This data could be used as reference data during the follow-up visits. The maximum difference between the measured timing between the present setup and traditional NHPT is about 6.7%. It is important to note that, due to inherent delay (response time) in the traditional NHPT, when compared to present setup the measured timing is always on the higher side. Nondependency on the manual stopwatch to record the time and hands-free of any wearable device are the advantages of the present setup.
RESUMO
Objective: The current work aims to design and develop an automatically controlled wearable electrolarynx, a voice substitution device for laryngeal carcinoma survivals. Methods: The physical activity of mouth opening is sensed, amplified, and made to act as an enable signal to trigger the wearable electrolarynx. The resulting speech is recorded and compared for its voice reaction durations with that of manual electrolarynx and normal speaking methods. Perception evaluations of 5 subjects from 10 speech-language therapists are obtained. Results: The wearable electrolarynx turn-on in 13 µs once the mouth movement for speech is sensed. The voice initiation time and termination durations are 215.68 m and 231.41 ms, respectively. Results indicate that there is no significant difference (P < 0.05) between the voice reaction durations of wearable electrolarynx and normal speaking methods. The subjective evaluation results show that there is a significant improvement (P < 0.05) in intelligibility and noise reduction when compared to a commercially available electrolarynx with an average intra-class correlation coefficient of 0.68 from analysis of variance two factors without replication. Conclusions: The assessment of the wearable and automatically controlled electrolarynx provides hands-free speech and easy control over the device.
RESUMO
This paper presents the design, simulation and low-cost fabrication of microfluidic channel for biomedical application. Channel is fabricated using soft lithography technique. Printed Circuit Board (PCB) is used to make the master for the channel. Channel pattern is transferred on PCB plate using toner transfer technique followed by ferric chloride etching. Paper also discusses, the issues involved in PCB based master fabrication and their viable solutions. Glass is used as substrate material and the channel is made of Sylgard 184 Polydimethylsiloxane (PDMS). Channel is interfaced with a syringe pump to observe the fluid flow. To predict the behavior of the channel, FEM simulation is performed using COMSOL Multiphysics 5.2a. There is a good match between the theoretical, simulation and test results. Finally, to test the biocompatibility of the channel, genomic DNA is passed through the channel and gel electrophoresis analysis is performed.
