Assuntos
Antifúngicos/efeitos adversos , Hipoglicemia/induzido quimicamente , Hipoglicemiantes/efeitos adversos , Candidíase/tratamento farmacológico , Diabetes Mellitus/tratamento farmacológico , Interações Medicamentosas , Feminino , Fluconazol/efeitos adversos , Glibureto/efeitos adversos , Humanos , Pessoa de Meia-IdadeRESUMO
This report deals with a young girl with Duane's retraction syndrome who also had left facial hemiatrophy (Parry-Romberg syndrome). Report of such an association is probably first of its type to be documented in literature.
Assuntos
Síndrome da Retração Ocular/complicações , Hemiatrofia Facial/complicações , Criança , Feminino , HumanosAssuntos
Cálcio/sangue , Digitalis , Insuficiência Cardíaca/sangue , Magnésio/sangue , Plantas Medicinais , Plantas Tóxicas , Potássio/sangue , Sódio/sangue , Adolescente , Adulto , Idoso , Criança , Diuréticos/uso terapêutico , Feminino , Insuficiência Cardíaca/terapia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
A quantitative assessment of post-ischaemic paraesthesiae has been made in 50 pellagrins and 20 healthy identical controls. The results show a higly significant diminution of the paraesthetic response in pellagrins. In pellagrins having peripheral neuropathy the depression of paraesthesiae was more marked than in those without peripheral neuropathy. There was no consistent relationship between severity of peripheral neuropathy and degree of depression of paraesthetic response.
Assuntos
Pelagra/fisiopatologia , Nervos Periféricos/fisiopatologia , Adolescente , Adulto , Idoso , Braço/irrigação sanguínea , Feminino , Humanos , Isquemia/fisiopatologia , Masculino , Pessoa de Meia-Idade , Parestesia/etiologia , Pelagra/complicações , Doenças do Sistema Nervoso Periférico/complicações , Doenças do Sistema Nervoso Periférico/fisiopatologiaRESUMO
In 25 cases of pellagra and 10 healthy controls, the blood pyruvic acid levels in the fasting stage and after 60 and 90 minutes of glucose load were estimated by the technique of Friedmann & Haugen (1943). The blood pyruvic acid levels after 60 and 90 minutes of glucose load were significantly higher in pellagrins as compared to controls. The following conclusions were drawn from this study: (i) that there is impairment of pyruvic acid metabolism in cases of pellagra, which is more marked in pellagrins with neurological manifestations than in those without; (ii) that after administration of nicotinic acid alone for 15 days the pyruvic acid levels returned to normal, thereby indicating that nicotinic acid deficiency is the cause of deranged pyruvate metabolism; (iii) that there is significant improvement in neurological status after nicotinic acid therapy.