RESUMO
Osler-Weber-Rendu syndrome is an uncommon vascular disorder inherited as an autosomal dominant trait with varying penetrance and expression. A multidisciplinary approach is used for a detailed diagnostic workup and management based on the patient's symptoms at presentation.
RESUMO
Vogt-Koyanagi-Harada disease is a multisystem autoimmune inflammatory disorder that affects the eyes, ears, skin, and the nervous system. It is a rare disease that mainly affects Asian, Hispanic, and Middle Eastern populations. Systemic steroids and immunosuppressants are frequently used to treat autoimmune diseases like this. Despite the fact that they reduce morbidity, immunosuppressants can have a number of side effects and are difficult to use, particularly when treating uncommon autoimmune illnesses. We present a case of a 56-year-old man who visited our health facility complaining of increased tears in both eyes along with bilateral blurring of vision. He was subsequently identified as having Vogt-Koyanagi-Harada disease. After prednisolone and methotrexate failed to have the desired effect, he was treated with azathioprine, which caused pancytopenia, and manifested as fever with positive blood culture for a coagulase-negative staphylococcus infection. Keywords: case reports; pancytopenia; steroid.
Assuntos
Pancitopenia , Síndrome Uveomeningoencefálica , Masculino , Humanos , Pessoa de Meia-Idade , Azatioprina/efeitos adversos , Síndrome Uveomeningoencefálica/induzido quimicamente , Síndrome Uveomeningoencefálica/diagnóstico , Síndrome Uveomeningoencefálica/tratamento farmacológico , Pancitopenia/induzido quimicamente , Prednisolona/uso terapêutico , Imunossupressores/efeitos adversosRESUMO
Acute pancreatitis can trigger a systemic inflammatory response leading to wide range of complications that could be local or systemic. Viruses have been implicated in most of the infective etiology of acute pancreatitis. Cranial nerve palsy in acute pancreatitis patient is a rare event. A 35-year-old male had mild pancreatitis which resolved with treatment. After a week of admission, he developed right sided facial palsy which gradually improved with oral steroids, acyclovir, and physiotherapy. Whether it was a complication of acute pancreatitis or a mere co-existence secondary to some infective cause could not be proven. Keywords: Acute pancreatitis; facial nerve palsy; viruses.
