Primary squamous cell carcinoma of thyroid gland-First case report from state Punjab, India.

Primary squamous cell carcinoma of the thyroid is a very rare thyroid malignancy. In addition, due to its presentation as a locally advanced disease with a high tendency to metastasize, it has a poor prognosis and outcome. We report a 60-year-old male patient with PSCC, which was confirmed by immunohistochemistry on biopsy. The patient was staged as T4N1M0 and was planned as per the multidisciplinary team approach. In sum, pathologic examination and IHC aid in distinguishing this lesion and help in differentiating it from other tumors of similar histology. Furthermore, it also aids in planning treatment.

Autonomous Functioning Thyroid Nodule in a 4-year-old Male Child Treated with Radioiodine (I-131).

Autonomous functioning thyroid nodules that cause toxic manifestations (toxic adenomas) are benign monoclonal tumors characterized by their capacity to grow and produce thyroxine (T4) and triiodothyronine (T3) autonomously, i.e. in the absence of thyrotropin thyroid stimulating hormone. Toxic adenomas are a rare presentation of hyperthyroidism in the pediatric population. Radioiodine (I-131) has been widely used for therapy of patients with toxic adenomas and is now accepted as a safe and effective treatment even in the pediatric age group. The authors here present a case of a 4-year-old boy with a solitary hyperfunctioning thyroid nodule, who was successfully treated with radioiodine (I-131) and is presently on follow-up.