Perturbations in gut microbiota composition in schizophrenia.

Schizophrenia is a severe, complex and long-term psychiatric disorder with unclear etiology. Gut microbes influence the central nervous system via the gut-brain axis. Consequently, investigations of the relationship between gut microbes and schizophrenia are warranted. This study involved 29 patients with schizophrenia and 30 age-matched normal controls. After 16S rRNA gene sequencing and whole-genome shotgun metagenomic sequencing, we analyzed microbial diversity, composition, and function. According to 16S rRNA and metagenomic gene sequencing results, patients with schizophrenia had higher abundances of Clostridium and Megasphaera. Functional analysis showed that sphingolipid, phosphonates and phosphinates, as well as glutamine metabolism were associated with the occurrence and development of schizophrenia. Our data suggest that the gut microbiota exerts an effect on patients with schizophrenia, providing valuable insights into the potential regulation of in the context of this disorder.

A Survey on Artificial Intelligence Aided Internet-of-Things Technologies in Emerging Smart Libraries.

With the boom in artificial intelligence (AI) and Internet-of-Things (IoT), thousands of smart devices are interconnected with each other and deeply applied into human society. This prosperity has significantly improved public service and management, which were traditionally based on manual work. As a notable scenario, librarianship has embraced an era of "Smart Libraries" enabled by AI and IoT. Unlike existing surveys, our work comprehensively overviews the AI- and IoT-based technologies in three fundamental aspects: smart service, smart sustainability, and smart security. We then further highlight the trend towards future smart libraries.