1.
Org Lett
; 8(12): 2547-50, 2006 Jun 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16737310
RESUMO
Mediated by copper acetate, an efficient approach to the C-N bond formation via direct aminolysis of dithioacetals 2 and 5 with ammonia, primary or secondary amines are developed under mild conditions. Enaminones 3 and 6 were thus obtained in high to excellent yields with high chemoselectivity. This type of aminolysis reaction presents a new synthetic application of the dithioacetal functionality. [reaction: see text]