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1.
Vopr Onkol ; 60(1): 52-5, 2014.
Artigo em Russo | MEDLINE | ID: mdl-24772617

RESUMO

Aim of this study was to analyze the karyological indicators in exfoliated cells in patients with cancer of the gastrointestinal tract. There was revealed statistically significant (p < 0.01) increase of all parameters in buccal and nasal epithelium in such kind of patients compared to healthy persons. These changes were systemic in nature and reflected the general state of the organism.


Assuntos
Neoplasias Gastrointestinais/genética , Neoplasias Gastrointestinais/terapia , Cariótipo , Cariotipagem , Adulto , Idoso , Neoplasias Colorretais/genética , Neoplasias Colorretais/terapia , Análise Citogenética , Feminino , Neoplasias Gastrointestinais/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Mucosa Bucal/patologia , Neoplasias Gástricas/genética , Neoplasias Gástricas/terapia
2.
Vopr Onkol ; 55(1): 51-5, 2009.
Artigo em Russo | MEDLINE | ID: mdl-19435200

RESUMO

Administration of an immunomodulator, galavit, for stage II-III non-small lung cancer along with standard therapy was followed by immunological vigor improvement by the end of the course. CD3, CD4, IgA, IgM and IgG indices were normal in more than 80% of the study group by day 51 after surgery; CD8, CD20 and HLA-DR--in more than 50%; CD16--in 45.2%. In control, by day 51, normal IgG and HLA-DR levels were reported in 60%. The remaining indices were normal in less than 50%. Our results point to immunological vigor improvement due to use of galavit. The drug is well tolerated, has neither side effects nor toxicity.


Assuntos
Antígenos de Neoplasias/sangue , Carcinoma Pulmonar de Células não Pequenas/imunologia , Fatores Imunológicos/uso terapêutico , Neoplasias Pulmonares/imunologia , Ftalazinas/uso terapêutico , Adulto , Idoso , Antígenos CD20/sangue , Complexo CD3/sangue , Antígenos CD4/sangue , Antígenos CD8/sangue , Carcinoma Pulmonar de Células não Pequenas/patologia , Método Duplo-Cego , Feminino , Antígenos HLA-DR/sangue , Humanos , Imunoglobulina A/sangue , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Fatores Imunológicos/farmacologia , Luminol/análogos & derivados , Neoplasias Pulmonares/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Ftalazinas/farmacologia , Receptores de IgG/sangue
4.
Vestn Rentgenol Radiol ; (5): 29-38, 2002.
Artigo em Russo | MEDLINE | ID: mdl-12622036

RESUMO

The results of examination of 156 patients were used to consider whether radiation and endoscopic techniques might be used in the differential diagnosis of gastric ulcerations. The necessity of their complex use is shown. Evidence is provided for that the understanding of intramural changes at the site of ulceration should underlie the interpretation of visual changes in the gastric mucosa. An algorithm has been developed for the rational and effective use of radiation and endoscopic techniques in the differential diagnosis of gastric ulcerations. The algorithm is shown to be highly effective in the correct interpretation of the pattern of an identified ulceration (98.4% specificity). Ultrasound and computed tomographic semiotics of benign and malignant gastric ulcerations is presented.


Assuntos
Gastroscopia , Neoplasias Gástricas/diagnóstico , Úlcera Gástrica/diagnóstico , Estômago/diagnóstico por imagem , Algoritmos , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Neoplasias Gástricas/diagnóstico por imagem , Úlcera Gástrica/diagnóstico por imagem , Ultrassonografia
7.
Vopr Onkol ; 38(7): 818-23, 1992.
Artigo em Russo | MEDLINE | ID: mdl-1338674

RESUMO

A procedure for obtaining microcirculation coefficient is described. It is based on the phenomenon of formation of a focus of radionuclide hyperfixation on scintigrams of tumor area due to embolization of its arterioles and precapillaries with radionuclide. The method was used in 26 breast cancer patients before neoadjuvant chemotherapy. A direct correlation between the microcirculation coefficient and degree of tumor-induced pathomorphosis of tumor cells was established. The coefficient values proved more or less predictive of tumor response to chemotherapy.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias da Mama/irrigação sanguínea , Neoplasias da Mama/tratamento farmacológico , Adulto , Neoplasias da Mama/diagnóstico por imagem , Quimioterapia Adjuvante , Ciclofosfamida/administração & dosagem , Doxorrubicina/administração & dosagem , Avaliação de Medicamentos , Embolização Terapêutica , Feminino , Fluoruracila/administração & dosagem , Humanos , Microcirculação/diagnóstico por imagem , Pessoa de Meia-Idade , Prognóstico , Cintilografia , Pertecnetato Tc 99m de Sódio , Fatores de Tempo
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