RESUMO
In article seven-year experience of treatment 126 sick mitral heart diseases to which have been implanted domestic monofolding the MIKS and folding MEDING-2 and ROSCARDIKS artificial mitral valve. At a comparative estimation of a haemodynamic efficiency and the analysis of frequency of occurrence of dysfunctions of the specified mechanical artificial valve it is revealed, that till three years the postimlantsperiod implant the MIKS and MEDING-2 possess advantage over ROSCARDIKS on haemodynamic properties, despite priority ROSCARDIKS on a standard size. It is shown, that initially low diastolic pressure gradient on mitral artificial valve and initially big area effective apertures mitral artificial valve have crucial importance in aspect of preventive maintenance of formation valve complications and reduction of number of repeated operations by open heart.
Assuntos
Próteses Valvulares Cardíacas , Estenose da Valva Mitral/fisiopatologia , Valva Mitral/fisiopatologia , Hemodinâmica/fisiologia , Humanos , Valva Mitral/anormalidades , Valva Mitral/cirurgia , Estenose da Valva Mitral/terapiaRESUMO
The possibility of the prolonged conservation of the native erythrocyte state of the donor erythrocyte mass with the use of barbotage aeronization was shown. The method of barbotage aero ionization, which was proposed by us in order to prolong the period of storage of donor erythrocytes, allows to decrease the level of destructive processed in storable erythrocyte mass, with the evidence of decrease in intensity of peroxidase lipid oxidation and growth of antioxidant activity in it.
Assuntos
Antioxidantes/metabolismo , Preservação de Sangue , Eritrócitos/metabolismo , Metabolismo dos Lipídeos , Eritrócitos/citologia , Humanos , OxirreduçãoAssuntos
Antioxidantes/farmacologia , Preservação de Sangue/métodos , Eritrócitos/efeitos dos fármacos , Peroxidação de Lipídeos/efeitos dos fármacos , Picolinas/farmacologia , Antioxidantes/metabolismo , Doadores de Sangue , Catalase/metabolismo , Eritrócitos/enzimologia , Eritrócitos/metabolismo , Humanos , Compostos Orgânicos/química , Compostos Orgânicos/farmacologia , Conservantes Farmacêuticos/química , Conservantes Farmacêuticos/farmacologia , Fatores de TempoAssuntos
Empiema Pleural/terapia , Endotoxemia/terapia , Abscesso Pulmonar/terapia , Plasmaferese/métodos , Doença Aguda , Antibacterianos/uso terapêutico , Lavagem Broncoalveolar , Terapia Combinada , Intervalo Livre de Doença , Empiema Pleural/complicações , Empiema Pleural/mortalidade , Endotoxemia/etiologia , Endotoxemia/mortalidade , Humanos , Fatores Imunológicos/uso terapêutico , Abscesso Pulmonar/complicações , Abscesso Pulmonar/mortalidade , Resultado do TratamentoRESUMO
Under study were catalase activity and indicators of lipid peroxidation (LP) of donor blood exposed to different doses of UV irradiation. Doses lower than 630 J/m2 were found to activate catalase and to inhibit LP while doses higher than 630 J/m2 inhibited catalase activity and activated LP. The indicators of LP have confirmed that therapeutic doses of UV-irradiated blood were nontoxic. The most optimal therapeutic dose of irradiation (630 J/m2) was determined.
