RESUMO
Cerebral tumours are a cause of seizures in less than 1-2% of children epilepsy. Seizure symptoms usually precede the diagnosis by several years and are often the only symptoms of an ongoing process. The symptomatology of the seizures often correlates with localization of a neoplastic lesion. The authors present six children aged 3 to 18 in whom epileptic seizures not susceptible to treatment were caused by cerebral tumours. The duration of epilepsy until the determining of the aetiology was various--from half a year to 13 years. In each of our six patients focal epilepsy occurred with simple or complex seizures with secondary generalization. It was only one patient in whom the tomography of the head turned out to be sufficient enough to establish the diagnosis of a brain tumour; in the other ones MR was necessary. The final diagnosis in four of the children was supported by histopathologic examination carried out during a neurosurgical procedure, whereas in one of them--by means of biopsy of the brain.
Assuntos
Neoplasias Encefálicas/complicações , Epilepsia/etiologia , Epilepsia/patologia , Adolescente , Neoplasias Encefálicas/patologia , Criança , Pré-Escolar , Eletroencefalografia , Epilepsia/fisiopatologia , Feminino , Humanos , Imageamento por Ressonância Magnética , Masculino , Índice de Gravidade de DoençaRESUMO
In the recent years the number of diagnosed cases of Lyme Disease has tended to increase. This is due to the possibility of serological examinations. Between 1992-95 at the Neurological Department of 2nd Chair of Pediatrics Silesian Medical Academy in Katowice 7 children with Lyme Disease were hospitalized. The authors analysed the clinical course, important laboratory and serological data and treatment effects.
Assuntos
Doença de Lyme/epidemiologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Imunoglobulina G/imunologia , Imunoglobulina M/imunologia , Doença de Lyme/imunologia , Masculino , Polônia/epidemiologiaRESUMO
A case of Leigh disease in a 3-year-old girl is reported. The child had regression of the psychomotor development, muscular hypotonia, weak tendinous reflexes, opsoclonus, tremor of the whole body, hypertrichosis, autonomic system disturbances. Laboratory investigations demonstrated raised serum lactic acid level. Postmortem histological examination of the brain confirmed the diagnosis of Leigh disease established before death.