RESUMO
A 10-year-old girl demonstrated advanced choroideremia. She had decreased visual acuity, high myopia, and characteristic fundus findings of choroideremia. Her ERG, dark adaptation, visual fields, and fluorescein angiogram were all abnormal; the results were consistent with choroideremia. Her chromosome studies revealed that she was a genotypically normal female. Her parents were examined ophthalmologically and found to be normal.
Assuntos
Corioide/patologia , Angiografia , Criança , Feminino , Fundo de Olho/patologia , Humanos , Cariotipagem , Miopia/etiologia , Cegueira Noturna/etiologia , Cegueira Noturna/patologia , Epitélio Pigmentado Ocular/patologia , Doenças da Úvea/genética , Doenças da Úvea/patologia , Acuidade VisualRESUMO
Following controlled ocular penetrating injuries in rabbits, autologous blood was injected into the vitreous. All animals were examined with ultrasonography, ophthalmoscopy and photography. After 3 weeks the animals were sacrificed and serial histologic sections were made on the enucleated globes. Fibroblasts and collagen were found in the vitreous. In additional eyes, the altered vitreous was removed and examined by gel electrophoresis following limited pepsin digestion. Type I collagen was an important component of vitreous fibrosis. In contrast, only type II collagen was detected in normal vitreous. The collagen formation after hemorrhagic injury may follow a similar process of wound healing in other tissues.
Assuntos
Colágeno/metabolismo , Traumatismos Oculares/metabolismo , Corpo Vítreo/metabolismo , Ferimentos Penetrantes/metabolismo , Animais , Colágeno/classificação , Eletroforese em Gel de Poliacrilamida , Oftalmopatias/etiologia , Traumatismos Oculares/complicações , Traumatismos Oculares/patologia , Feminino , Fibroblastos/patologia , Hemorragia/etiologia , Masculino , Coelhos , Descolamento Retiniano/etiologia , Ultrassonografia , Ferimentos Penetrantes/complicaçõesRESUMO
Two patients who had laser iridotomy performed for pupillary block glaucoma developed hypopyon following surgery. One case had iris bombé with rubeosis iridis, and the other had chronic angle closure glaucoma. Factors contributing to inflammation and possible hypopyon following laser iridotomy are discussed.