[Myoepitheliomas of the palate]. / Gruczolak z komórek mioepitelialnych podniebienia.

The authors present a case of myoepithelioma of the palate. Frequency, treatment and pathologic diagnosis of the disease are discussed. A Polish name of the disease is suggested.

[Familial LCAT deficiency--clinical picture. Case report]. / Rodzinny niedobór LCAT--obraz kliniczny. Opis przypadku.

We report a case of familial LCAT deficiency, diagnosed in a 35 year old women. The disease manifested itself by a presence of proteinuria, corneal opacities and haemolytic anaemia with target cells. Suspecion of familial LCAT deficiency was based on renal biopsy, which revealed characteristic serpiginous fibrillar deposits in electron microscopy. The diagnosis was confirmed by a marked decrease of estrified cholesterol, low HDL-cholesterol concentration, decrease of LCAT activity in serum, typical "stacked coins" picture of HDL lipoproteins in electron microscopy examination and positive familial history--diagnosis of LCAT deficiency in dialysed brother of patient.

Fabry's disease. Report of the case diagnosed on the basis of routine ultrastructural examination of the renal biopsy.

A 45-year-old man who developed proteinuria was diagnosed as having Fabry's disease on the basis of renal histological findings and prominent decreases in alpha-galactosidase A activity in blood leukocytes.

Tracheobronchial amyloidosis.

The authors have described eleven cases of tracheobronchial amyloidosis, in 6 men and 5 women with a mean age of 58.7 years. The follow-up period ranged from several month to six years. The clinical picture and histopathological changes in bronchoscopic and postmortem sections in two patients were described. In all cases immunohistochemical examinations for the presence of amyloid AA, AL, transthyretin (prealbumin) and beta 2-microglobulin were performed. In six cases the presence of transthyretin was found. The remaining reactions were negative. Resorptive giant cells reaction to amyloid was observed in 3 transthyretin positive cases and 1 transthyretin negative case. Four cases with negative amyloid in the examination for the presence of transthyretin accompanied bronchial carcinoma, all these cases were men with a mean age of 63.0 years.

Thymomas and thymic carcinomas. Evaluation of the Müller-Hermelink classification.

In the present study the Müller-Hermelink classification was used to analyze 39 thymomas and 4 thymic carcinomas collected over 20 years at the Chair and Department of Pathomorphology CM UJ. Our series consisted of 10 medullary thymomas (25.6%), 13 mixed (33.3%), 7 organoid (17.9%) and 9 cortical thymomas (23.0%). The mean age of the patients was 50.3 and it was the highest in patients with mixed thymomas-58.4 years and the lowest in patients with organoid thymomas-38.9 years, the difference being statistically significant. In the present series women were predominant (24:15). Myasthenia gravis was observed in 10 patients (25.6%), 5 women and 5 men, in 7 of them it was associated with cortical and organoid thymomas. Medullary, mixed and organoid thymomas were usually of lower stage (I and II), having a better prognosis than cortical thymomas and thymic carcinomas. One organoid thymoma recurring after 7 years evolved into cortical thymoma. Two thymic carcinomas were diagnosed as anaplastic, low differentiated, one as sarcomatous and one as well differentiated squamous carcinoma. The mean age of the patients was 39.7 years. The prognosis in all the patients with thymic carcinoma was poor. Based upon personal experience the authors regard the Müller-Hermelink classification as useful, easy to apply, reproducible and providing important prognostic information.

[Late complications after ethylene glycol poisoning--case history]. / Pózne powiklania po zatruciu glikolem etylenowym--opis przypadku.

Late complications after ethylene glycol intoxication in a 39 years old patient were presented. Irreversible severe renal failure and persistent symptoms of peripheral nerve system damage dominated in the clinical manifestation.

Squamous cell carcinoma arising in an odontogenic cyst. Report of three cases.

Primary intraosseous carcinoma of the jaws is an uncommon lesion. The majority of these develop in preexisting odontogenic cysts. Three cases of primary intraosseous squamous cell carcinomas of the mandible and maxilla, with evidence of origin in the odontogenic cysts are described. The recent literature on carcinomas arising in jaws cysts is reviewed.

The malignant form of calcifying odontogenic cyst. A case report.

A rare case of the malignant form of Gorlin's cyst is reported in a 42-year-old woman. The neoplasm developed in the right maxilla, infiltrated the anterior wall and roof of the sinus and grew into the nasal cavity. Based upon literature data we characterized various clinical and histological forms of Gorlin's cyst (calcifying odontogenic cyst).

[Odontogenic cysts--histogenesis, histology, potential for possible neoplastic transformation]. / Torbiele zebopochodne--histogeneza, histologia, potencjalne mozliwosci transformacji nowotworowej.

Epithelial odontogenic cyst develop either in result od peridental inflammation-radicular cyst, or in result of developmental disturbances in the course of the odontogenesis. The latter are divided into primordial and dentigerous cysts. Some odontogenic cysts are lined with squamous keratotic epithelium -ortho- or parakeratotic type. The latter is characterized by higher recurrence rate and malignant potential. Primary intraosseous carcinoma (PIOC) both keratizing and nonkeratizing might originate in keratocyst. Mucoepidermoid carcinoma and occasionally other benign and malignant sialogenic tumors might originate in keratocyst either. In addition in the jaw-bones with the odontogenic cyst or even without the cyst, squamous odontogenic tumor (SOT) can develop or so-called squamous odontogenic tumor-like proliferation in odontogenic cyst (SOT-LPOC). PIOC is a cancer of low grade malignant potential. Biology of SOT and SOT-LPOC in not elucidated yet as these are not frequently occurred lesion.

[A case of amyloidosis of the larynx]. / Przypadek guza skrobiawiczego krtani.

A case of surgically treated amyloidosis of the larynx is presented. Current opinions on the structure of amyloid are given.

[Pathogenesis and histologic diagnosis of carcinoid tumor of the stomach]. / Patogeneza i diagnostyka histologiczna rakowiaków zoladka.

Gastric carcinoids are reviewed in respect of epidemiology, histogenesis, localization, hormonal aspects and malignancy. Coexistence of gastric carcinoids and gastric carcinomas is also discussed as well as optimalization of histologic histochemical and ultrastructural diagnosis of gastric carcinoids.

Dendritic cells in bronchial adenocarcinoma.

We studied 28 bronchial adenocarcinomas (including 11 bronchiolo-alveolar carcinomas) stained for S-100 protein by the PAP technique in order to visualize dendritic cells in the neoplastic area. Dendritic cells were found in all cases varying in number from single to multiple and from region to region. Bronchiolo-alveolar carcinomas contained a similar quantity of these cells. The most numerous dendritic cells up to several scores per microscopical low-power field almost in all fragments of the tumour were found in three adenocarcinomas with numerous foci of the squamous cell metaplasia. Normal and metaplastic squamous epithelium of the bronchial mucosa did not show the presence of dendritic cells.