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1.
Am J Surg ; 220(6): 1480-1484, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33046221

RESUMO

BACKGROUND: Base Deficit (BD) and lactate have been used as indicators of shock and resuscitation. This study was done to evaluate the utility of BD and lactate in identifying shock and resuscitative needs in trauma patients. METHODS: A prospective observational study was performed from 3/2014-12/2018. Data included demographics, admission systolic BP, ISS, BD, lactate, blood transfusion, and outcomes. BD and lactate were modeled continuously and categorically and compared. RESULTS: 2271 patients were included. BD and lactate were moderately correlated (r2 = 0.63 p < 0.001). On univariate regression, BD and lactate were associated with transfusion requirement and mortality (p < 0.001), but on multivariate regression, only BD was associated with transfusion requirement and mortality (OR = 1.2, p < 0.001; OR = 1.1, p < 0.001, respectively). BD discriminated better than lactate for hypotension, higher ISS, increased transfusion requirements and mortality. CONCLUSIONS: Admission BD and lactate levels are correlated following injury, but BD is superior to lactate in identifying shock, resuscitative needs and mortality in severely injured trauma patients.


Assuntos
Desequilíbrio Ácido-Base/sangue , Ácido Láctico/sangue , Ressuscitação , Choque/sangue , Choque/terapia , Ferimentos e Lesões/sangue , Ferimentos e Lesões/terapia , Biomarcadores/sangue , Transfusão de Sangue , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Estudos Prospectivos , Choque/mortalidade , Índices de Gravidade do Trauma , Ferimentos e Lesões/mortalidade
2.
Am J Surg ; 220(6): 1503-1505, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32980078

RESUMO

BACKGROUND: Levetiracetam and phenytoin are comparable for acute posttraumatic seizure(PTS) prophylaxis. Levetiracetam-induced hyponatremia has been reported in non-trauma patients. We studied hyponatremia in posttraumatic intracranial hemorrhage(ICH) patients receiving either drug. METHODS: Retrospective review of patients with ICH receiving PTS prophylaxis was performed. Patients were categorized by degree of sodium nadir: normal, mild, moderate, or severe, and analyzed by levetiracetam versus phenytoin. Patients were matched 2:1 regarding age and injury severity score(ISS). Incidence and treatment for hyponatremia was examined. RESULTS: 1735 ICH patients received PTS prophylaxis over an 8-year period. After exclusions and matching, there were 282 phenytoin and 564 levetiracetam patients. Age, ISS and initial sodium were comparable between the matched cohorts. There was no clinically significant difference in the rate or degree of hyponatremia. Treatment was more common in levetiracetam patients. DISCUSSION: There was a small but clinically insignificant difference in the incidence of hyponatremia in traumatic ICH patients receiving levetiracetam vs. phenytoin for PTS prophylaxis. There was an increased rate of intervention for hyponatremia in the levetiracetam group, possibly due to a coincidental preventive paradigm shift.


Assuntos
Anticonvulsivantes/efeitos adversos , Hiponatremia/induzido quimicamente , Hiponatremia/epidemiologia , Levetiracetam/efeitos adversos , Fenitoína/efeitos adversos , Convulsões/prevenção & controle , Adulto , Anticonvulsivantes/uso terapêutico , Lesões Encefálicas Traumáticas/complicações , Intervenção Médica Precoce , Feminino , Humanos , Incidência , Levetiracetam/uso terapêutico , Masculino , Pessoa de Meia-Idade , Fenitoína/uso terapêutico , Estudos Retrospectivos , Convulsões/etiologia , Adulto Jovem
3.
Trauma Surg Acute Care Open ; 3(1): e000159, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29766137

RESUMO

BACKGROUND: Successful non-operative management (NOM) of blunt splenic trauma is enhanced with splenic angioembolization (SAE). Patients may still require splenectomy post-SAE for splenic infarction/necrosis. Prior studies have used white blood cell count (WBC), platelet count (PLT), and PLT:WBC ratio after splenectomy to predict complications, but none have evaluated these findings prior to splenectomy in patients who have undergone SAE. Changes in these values may indicate clinically significant splenic infarction, facilitating management of these patients. METHODS: Patients admitted to an American College of Surgeons verified level 1 trauma center from January 2007 to August 2017 who underwent SAE were identified. Patients with successful NOM after SAE (SAE/NOM) were compared with those requiring splenectomy (SAE/SPLEN). Data included demographics, splenic injury grade, Injury Severity Score (ISS), time to SAE and splenectomy, intensive care unit and hospital length of stay (LOS), and complete blood count. Lab values were analyzed immediately post-SAE (time 1) and day 5 post-SAE (or day of discharge) for SAE/NOM patients and day of SPLEN for SAE/SPLEN patients (time 2). Data were analyzed using Mann-Whitney U, χ2 tests, and receiver operating characteristic (ROC) curves with significance attributed to P<0.05. RESULTS: Of 124 patients undergoing SAE, 16 (13%) later required SPLEN for infarction/necrosis at a median of 5 days post-SAE (IQR: 3-10 days). SAE/SPLEN and SAE/NOM patients did not differ by age, gender, ISS, or grade of splenic injury. SAE/SPLEN patients had longer hospital LOS (23 vs. 10 days, P<0.001). WBC, PLT, and PLT:WBC ratio did not differ between the groups at time 1. At time 2, WBC was higher and PLT:WBC ratio was lower in SAE/SPLEN patients. Using ROC curves at time 2, the area under the curve was 0.90 (P<0.001) for WBC and 0.71 (P<0.007) for PLT:WBC ratio. DISCUSSION: Patients requiring splenectomy for clinically significant infarction/necrosis after SAE develop leukocytosis and decreased PLT:WBC ratio when compared with SAE/NOM patients. Monitoring these parameters allows more prompt diagnosis and operative intervention. LEVEL OF EVIDENCE: Therapeutic/care management, level III.

4.
Am J Surg ; 212(3): 379-83, 2016 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-27255781

RESUMO

BACKGROUND: Post-extubation stridor is an uncommon complication in medical intensive care units (ICUs) but has not been well studied in trauma patients. We sought to determine the incidence of reintubation due to stridor in trauma patients and describe associated risk factors. METHODS: A retrospective review of all intubated trauma patients was performed. Data collected included presence of stridor, demographic data, and details of intubation and extubation. RESULTS: Of all trauma patients reintubated, 31% were for stridor. Although female gender, age less than 18, blunt mechanism, and duration of intubation 5 days or more were associated with reintubation for stridor, endotracheal tube diameter was not. Mortality was not increased with reintubation. CONCLUSIONS: Trauma ICU patients are reintubated for stridor at a higher rate than medical ICU patients. Age, gender, blunt mechanism, and duration of intubation are risk factors for this complication.


Assuntos
Extubação , Unidades de Terapia Intensiva , Intubação Intratraqueal/efeitos adversos , Doenças da Laringe/etiologia , Sons Respiratórios/etiologia , Centros de Traumatologia , Ferimentos e Lesões/terapia , Adulto , California/epidemiologia , Feminino , Seguimentos , Humanos , Incidência , Doenças da Laringe/epidemiologia , Masculino , Estudos Prospectivos , Medição de Risco , Fatores de Risco
5.
J Am Coll Surg ; 219(4): 599-605, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25127510

RESUMO

BACKGROUND: Isolated free fluid (FF) on abdominal CT in stable blunt trauma patients can indicate the presence of hollow viscus injury. No criteria exist to differentiate treatment by operative exploration vs observation. The goals of this study were to determine the incidence of isolated FF and to identify factors that discriminate between patients who should undergo operative exploration vs observation. STUDY DESIGN: A review of blunt trauma patients at a Level I trauma center from July 2009 to March 2012 was performed. Patients with a CT showing isolated FF after blunt trauma were included. Data collected included demographics, injury severity, physical examination, CT, and operative findings. RESULTS: Two thousand eight hundred and ninety-nine patients had CT scans, 156 (5.4%) of whom had isolated FF. The therapeutic operative group included 13 patients; 9 had immediate operation and 4 failed nonoperative management. The nonoperative/nontherapeutic operation group consisted of 142 patients with successful nonoperative management and 1 patient with a nontherapeutic operation. Abdominal tenderness was documented in 69% of the therapeutic operative group and 23% of the nonoperative/nontherapeutic group (odds ratio = 7.5; p < 0.001). The presence of a moderate to large amount of FF was increased in the therapeutic operative group (85% vs 8%; odds ratio = 66; p < 0.001). CONCLUSIONS: Isolated FF was noted in 5.4% of stable blunt trauma patients. Blunt trauma patients with moderate to large amounts of FF without solid organ injury on CT and abdominal tenderness should undergo immediate operative exploration. Patients with neither of these findings can be safely observed.


Assuntos
Traumatismos Abdominais/diagnóstico por imagem , Ascite/diagnóstico por imagem , Tomada de Decisões , Laparotomia , Tomografia Computadorizada Multidetectores , Radiografia Abdominal/métodos , Ferimentos não Penetrantes/diagnóstico por imagem , Traumatismos Abdominais/complicações , Traumatismos Abdominais/cirurgia , Adulto , Ascite/etiologia , Ascite/cirurgia , Líquido Ascítico/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Seguimentos , Humanos , Masculino , Estudos Retrospectivos , Fatores de Tempo , Centros de Traumatologia , Ferimentos não Penetrantes/complicações , Ferimentos não Penetrantes/cirurgia
7.
J Trauma Acute Care Surg ; 75(2): 229-33, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23823613

RESUMO

BACKGROUND: The need for reintubation after weaning from mechanical ventilation (extubation failure) is associated with increased morbidity and mortality. In blunt trauma patients with pulmonary contusion, factors predicting successful weaning have not been reliably defined. The purpose of this study was to identify criteria predicting successful extubation in these patients. METHODS: Retrospective review during a 10-year period at a Level 1 trauma center was performed. A total of 173 extubations in 163 blunt trauma patients with pulmonary contusion requiring mechanical ventilation. Exclusion criteria include Glasgow Coma Scale (GCS) score of less than 9T before extubation, successful use of noninvasive positive-pressure ventilation after extubation, quadriplegia, and preextubation FIO2 of greater than 0.5. Data included age, Injury Severity Score (ISS), ventilator days, as well as GCS score, FIO2, the ratio of arterial oxygen tension to FIO2 (P/F ratio), and alveolar-arterial oxygen (A-a) difference at the time of extubation. Failure was defined as reintubation within 72 hours (excluding stridor or acute decline in GCS score). Mann-Whitney U-test, χ2 analysis, and logistic regression analysis determined variables associated with extubation failure. Odds ratios were used to compare P/F and A-a values associated with failed extubation. RESULTS: A total of 147 extubations (85%) were successful; 26 required reintubation. Patients did not differ by ISS, chest Abbreviated Injury Scale (AIS) score, presence of sternal or rib fractures, and admission pneumothorax or hemothorax. Increased age, A-a difference (≥ 120 mm Hg), and decreased P/F (<280) were associated with reintubation (p < 0.0001). By logistic regression analysis, P/F and A-a were independent variables for failed extubation; both remained independent risk factors when adjusted for age, ventilator days, GCS score, and preextubation FIO2. Using receiver operating characteristic curve inflection points for both P/F and A-a difference (area under the curve of 0.8 for both), patients with a P/F ratio less than 290 and an A-a difference of 100 mm Hg or greater were more likely to fail extubation (odds ratio, 9.2 and 8.7, respectively, p < 0.001). CONCLUSION: Blunt trauma patients with pulmonary contusion who are likely to fail extubation can be reliably identified using the readily available criteria of P/F ratio less than 290 and A-a difference of 100 mm Hg or greater.


Assuntos
Contusões/terapia , Lesão Pulmonar/terapia , Desmame do Respirador , Ferimentos não Penetrantes/terapia , Adulto , Distribuição de Qui-Quadrado , Humanos , Escala de Gravidade do Ferimento , Modelos Logísticos , Curva ROC , Respiração Artificial/estatística & dados numéricos , Estudos Retrospectivos , Estatísticas não Paramétricas , Falha de Tratamento , Desmame do Respirador/estatística & dados numéricos
8.
J Trauma ; 71(6): 1553-6, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22182866

RESUMO

BACKGROUND: Percutaneous tracheostomy is a routine procedure in the intensive care unit (ICU). Some surgeons perform percutaneous tracheostomies using bronchoscopy believing that it increases safety. The purpose of this study was to evaluate percutaneous tracheostomy in the trauma population and to determine whether the use of a bronchoscope decreases the complication rate and improves safety. METHODS: A retrospective review was completed from January 2007 to November 2010. Inclusion criteria were trauma patients undergoing percutaneous tracheostomy. Data collected included age, Abbreviated Injury Score by region, Injury Severity Score, ventilator days, and outcomes. Complications were classified as early (occurring within <24 hours) or late (>24 hours after the procedure). RESULTS: During the study period, 9,663 trauma patients were admitted, with 1,587 undergoing intubation and admission to the ICU. Tracheostomies were performed in 266 patients and 243 of these were percutaneous; 78 (32%) were performed with the bronchoscope (Bronch) and 168 (68%) without bronchoscope (No Bronch). There were no differences between the groups in Abbreviated Injury Score by region, Injury Severity Score, probability of survival, ventilator days, and length of ICU or overall hospital stay. There were 16 complications, 5 (Bronch) and 11 (No Bronch). Early complications were primarily bleeding (Bronch 3% vs. No Bronch 4%, not statistically significant). Late complications included tracheomalacia, tracheal granulation tissue, bleeding, and stenosis; Bronch 4% versus No Bronch 3%, (not statistically significant). One major complication occurred, with loss of airway and cardiac arrest, in the bronchoscopy group. CONCLUSION: Percutaneous tracheostomy was safely and effectively performed by an experienced surgical team both with and without bronchoscopic guidance with no difference in the complication rates. This study suggests that the use of bronchoscopic guidance during tracheostomy is not routinely required but may be used as an important adjunct in selected patients, such as those with HALO cervical fixation, obesity, or difficult anatomy.


Assuntos
Broncoscopia/métodos , Traumatismo Múltiplo/cirurgia , Traqueostomia/métodos , Adulto , Idoso , Broncoscopia/efeitos adversos , Estudos de Coortes , Cuidados Críticos/métodos , Feminino , Seguimentos , Humanos , Escala de Gravidade do Ferimento , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Traumatismo Múltiplo/diagnóstico , Complicações Pós-Operatórias/fisiopatologia , Estudos Retrospectivos , Medição de Risco , Traqueostomia/efeitos adversos , Centros de Traumatologia , Resultado do Tratamento
9.
J Vasc Surg ; 54(3): 857-9, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21571491
10.
J Trauma ; 70(5): 1038-42, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-19996792

RESUMO

BACKGROUND: Trauma activation for prehospital hypotension in blunt trauma is controversial. Some patients subsequently arrive at the trauma center normotensive, but they can still have life-threatening injuries. Admission base deficit (BD)≤-6 correlates with injury severity, transfusion requirement, and mortality. Can admission BD be used to discriminate those severely injured patients who arrive normotensive but "crump," (i.e., become hypotensive again) in the Emergency Department? The purpose is to determine whether admission BD<-6 discriminates patients at risk for future bouts of unexpected hypotension during evaluation. METHODS: Retrospective chart review was performed on all blunt trauma admissions at a Level I trauma center from August 2002 through July 2007. Hypotension was defined as a systolic blood pressure≤90 mm Hg. Patients who were hypotensive in the field but normotensive upon arrival in the emergency department (ED) were included. Age, gender, injury severe score, arterial blood gas analysis, results of focused abdominal sonogram for trauma (FAST), computed tomography, intravenous fluid administration, blood transfusions, and the presence of repeat bouts of hypotension were noted. Patients were stratified by BD≤-6 or ≥-5. Statistical analysis was performed using paired t test, χ, and logistic regression analysis with significance attributed to p<0.05. RESULTS: During the 5-year period, 231 blunt trauma patients had hypotension in the field with subsequent normotension on admission to the ED. Of these, 189 patients had admission BD data recorded. Patients with a BD≤-6 were significantly more likely to have repeat hypotension (78% vs. 30%, p<0.001). Overall mortality was 13% (24 of 189), but patients with repeat hypotension had greater mortality (24% vs. 5%, p<0.003). CONCLUSION: Blunt trauma patients with repeat episodes of hypotension have significantly greater mortality. Patients with transient field hypotension and a BD≤-6 are more than twice as likely to have repeat hypotension (crump). This study reinforces the need for early arterial blood gases and trauma team involvement in the evaluation of these patients. Patients with BD≤-6 should have early invasive monitoring, liberal use of repeat FAST exams, and careful resuscitation before computed tomography scanning. Surgeons should have a low threshold for taking such patients to the operating room.


Assuntos
Traumatismos Abdominais/complicações , Pressão Sanguínea , Serviços Médicos de Emergência/métodos , Hipotensão/etiologia , Ressuscitação/métodos , Centros de Traumatologia , Ferimentos não Penetrantes/complicações , Traumatismos Abdominais/epidemiologia , Traumatismos Abdominais/fisiopatologia , Adulto , California/epidemiologia , Seguimentos , Humanos , Hipotensão/epidemiologia , Hipotensão/fisiopatologia , Incidência , Escala de Gravidade do Ferimento , Estudos Retrospectivos , Taxa de Sobrevida , Ferimentos não Penetrantes/epidemiologia , Ferimentos não Penetrantes/fisiopatologia
12.
Artigo em Inglês | MEDLINE | ID: mdl-18948432

RESUMO

A 39-year-old man living with AIDS presented with a swollen face. He was found to be HIV infected after presenting with Coccidioides pneumonia 2 years previously and was placed on daily fluconazole and then on highly active antiretroviral therapy. Computed tomography confirmed superior vena cava obstruction secondary to lymphadenopathy. Biopsy confirmed coccidioidomycosis with no evidence of malignancy. To our knowledge, this is the first description of superior vena cave syndrome secondary to coccidioidomycosis and the first description of immune reconstitution inflammatory syndrome involving Coccidioides.


Assuntos
Coccidioidomicose/complicações , Síndrome Inflamatória da Reconstituição Imune , Doenças Linfáticas/complicações , Síndrome da Veia Cava Superior/complicações , Infecções Oportunistas Relacionadas com a AIDS/complicações , Adulto , Coccidioides , Coccidioidomicose/microbiologia , Infecções por HIV/complicações , HIV-1 , Humanos , Masculino , Síndrome da Veia Cava Superior/etiologia
13.
J Trauma ; 62(5): 1201-6, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17495725

RESUMO

BACKGROUND: To compare the effectiveness of supine versus prone kinetic therapy in mechanically ventilated trauma and surgical patients with acute lung injury (ALI) and adult respiratory distress syndrome (ARDS). METHODS: A retrospective review of all patients with ALI/ARDS who were placed on either a supine (roto-rest) or prone (roto-prone) oscillating bed was performed. Data obtained included age, revised trauma score (RTS), base deficit, Injury Severity Score (ISS), head Abbreviated Injury Scale score (AIS), chest (AIS), PaO2/FiO2 ratio, FiO2 requirement, central venous pressure (CVP), days on the bed, ventilator days, use of pressors, complications, mortality, and pulmonary-associated mortality. Data are expressed as mean+/-SE with significance attributed to p<0.05. RESULTS: From March 1, 2004 through May 31, 2006, 4,507 trauma patients were admitted and 221 were identified in the trauma registry as having ALI or ARDS. Of these, 53 met inclusion criteria. Additionally, 8 general surgery patients met inclusion criteria. Of these 61 patients, 44 patients were positioned supine, 13 were placed prone, and 4 patients that were initially placed supine were changed to prone positioning. There was no difference between the groups in age, CVP, ISS, RTS, base deficit, head AIS score, chest AIS score, abdominal AIS score, or probability of survival. The PaO2/FiO2 ratios were not different at study entry (149 vs. 153, p=NS), and both groups showed improvement in PaO2/FiO2 ratios. However, the prone group had better PaO2/FiO2 ratios than the supine group by day 5 (243 vs. 200, p=0.066). The prone group had fewer days on the ventilator (13.6 vs. 24.2, p=0.12), and shorter hospital lengths of stay (22 days vs. 40 days, p=0.08). There were four patients who failed to improve with supine kinetic therapy that were changed to prone kinetic therapy. These patients had significant improvements in PaO2/FiO2 ratio, and significantly lower FiO2 requirements. There were 18 deaths (7 pulmonary related) in the supine group and 1 death in the prone group (p < 0.01 by chi test). CONCLUSIONS: ALI/ARDS patients who received prone kinetic therapy had greater improvement in PaO2/FiO2 ratio, lower mortality, and less pulmonary-related mortality than did supine positioned patients. The use of a prone-oscillating bed appears advantageous for trauma and surgical patients with ALI/ARDS and a prospective, randomized trial is warranted.


Assuntos
Decúbito Ventral , Respiração Artificial/métodos , Síndrome do Desconforto Respiratório/terapia , Decúbito Dorsal , Adulto , Leitos , Humanos , Cinética , Pessoa de Meia-Idade , Síndrome do Desconforto Respiratório/etiologia , Estudos Retrospectivos , Procedimentos Cirúrgicos Operatórios/efeitos adversos , Resultado do Tratamento , Ferimentos e Lesões/complicações
14.
Am J Surg ; 190(6): 841-4, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16307931

RESUMO

BACKGROUND: Size of traumatic occult hemothorax on admission requiring drainage has not been defined. Computed axial tomography (CAT) may guide drainage criteria. METHODS: A retrospective review of patients with hemothoraces on CAT was performed. Extrapolating previously described methods of pleural fluid measurement, hemothoraces were quantified using the fluid stripe in the dependent pleural "gutter." Data included patient age, injury severity, and intervention (thoracentesis or tube thoracostomy). RESULTS: Seventy-eight patients with 99 occult hemothoraces met the criteria for study inclusion: 52 hemothoraces qualified as "minimal" and 47 as "moderate/large." Eight patients (15%) in the minimal group and 31 patients (66%) in the moderate/large group underwent intervention (P < .001). There was no difference in patient age, injury severity, ventilator requirement, or presence of pulmonary contusion. CONCLUSIONS: CAT in stable blunt-trauma patients can predict which patients with occult hemothorax are likely to undergo intervention. Patients with hemothorax > or = 1.5 cm on CAT were 4 times more likely to undergo drainage intervention compared with those having hemothorax < 1.5 cm.


Assuntos
Hemotórax/etiologia , Sangue Oculto , Fraturas das Costelas/complicações , Ferimentos não Penetrantes , Adulto , Drenagem , Feminino , Hemotórax/diagnóstico por imagem , Hemotórax/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia Torácica , Estudos Retrospectivos , Fraturas das Costelas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Índices de Gravidade do Trauma
16.
J Trauma ; 57(6): 1173-7, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15625446

RESUMO

INTRODUCTION: Patients with head injuries frequently have abnormal coagulation studies. Monitoring intracranial pressure (ICP) in head injured patients is common practice, but no best practice guidelines exist for coagulation parameters for ICP monitor placement. PURPOSE: To test the hypothesis that hemorrhagic complication rates from ICP monitor placement are low and that the use of FFP to correct coagulation parameters to "normal" is not indicated. METHODS: Retrospective review of all patients admitted to a Level I trauma center over a 3 year period, who underwent fiberoptic intraparenchymal ICP monitoring was undertaken. Inclusion criteria were coagulation studies (prothrombin time (PT), partial thromboplastin time (PTT), international normalized ratio (INR), platelet count) before ICP monitor placement and head CT scans to assess for hemorrhage before and after monitor placement. Data collected included age, Glasgow coma score (GCS), head region abbreviated injury score (H_AIS), time to ICP monitor placement, complications and outcomes. RESULTS: From 8/1/00 through 7/31/03, 5163 trauma patients were admitted, and 157 met inclusion criteria. Patients were stratified by INR, at the time of ICP placement as normal (0.8-1.2, 103 patients), borderline (1.3-1.6, 42 patients) and increased (>/=1.7, 12 patients). There was no difference between the groups in age, gender or H_AIS. Twenty two patients had component therapy to correct coagulopathy before ICP insertion, but 10 had INRs in the borderline group and 12 remained with INRs >/=1.7. Eleven patients had platelet counts 50,000-100,000 at ICP monitor placement, despite platelet transfusions. Time from admission to ICP monitor placement was significantly longer in patients who received component therapy (19.2 +/- 19.7 hours versus 8.8 +/- 13.9 hours, p < 0.002). Three patients had clinically insignificant, petechial hemorrhages (1.9%); one in each group, with INRs of 1.2, 1.3, and 2.5, respectively. CONCLUSIONS: In patients with INR

Assuntos
Transtornos da Coagulação Sanguínea/terapia , Transfusão de Sangue , Traumatismos Craniocerebrais/terapia , Hemorragias Intracranianas/prevenção & controle , Hipertensão Intracraniana/prevenção & controle , Monitorização Fisiológica/efeitos adversos , Adulto , Transtornos da Coagulação Sanguínea/etiologia , Traumatismos Craniocerebrais/complicações , Feminino , Tecnologia de Fibra Óptica , Humanos , Hemorragias Intracranianas/epidemiologia , Hemorragias Intracranianas/etiologia , Hipertensão Intracraniana/etiologia , Masculino , Monitorização Fisiológica/instrumentação , Plasma , Contagem de Plaquetas , Guias de Prática Clínica como Assunto , Estudos Retrospectivos , Estados Unidos/epidemiologia
17.
J Trauma ; 55(5): 860-3, 2003 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-14608157

RESUMO

BACKGROUND: Automated blood pressure (BP) determinations by oscillometry are reported to be as accurate as invasive monitoring for systolic pressures as low as 80 mm Hg. Automated BP devices are widely used by prehospital providers and in hospital operating rooms, emergency departments, and intensive care units, although the accuracy of automated BP has not been demonstrated in trauma patients. We hypothesized that automated BP is less accurate than manual BP in trauma patients. The purpose of this study was to determine the accuracy of automated BP versus manual BP in trauma patients. METHODS: A retrospective review of patients who met trauma activation criteria admitted to a Level I trauma center over a 30-month period was conducted. Patients were included if both manual BP and automated BP were measured within 5 minutes of admission. Additional data collected included Injury Severity Score, base deficit, and emergency department resuscitation volume. Statistical analysis was performed using paired t test, chi2, and linear regression analysis. Significance was attributed to a value of p < 0.05. RESULTS: From January 2000 through June 2002, 388 patients met inclusion criteria. Patients were grouped by manual BP levels: group 1, BP < or = 90 mm Hg (n = 92); group 2, BP 91-110 mm Hg (n = 119); and group 3, BP > or = 110 mm Hg (n = 177). The mean automated BP measurements were significantly higher than the manual measurements in groups 1 and 2 (26 and 16 mm Hg, respectively; p < 0.001). Of the 92 patients with manual BP < or = 90, 45 (49%) had automated BP > or = 100. The base deficit (-5, -3, and -2 for groups 1, 2, and 3, respectively; p < 0.01), Injury Severity Score (30, 25, and 18; p < 0.01), and volume of resuscitative fluid and blood (p < 0.001) all decreased with higher BP group. CONCLUSION: Injury severity, degree of acidosis, and resuscitation volume were more accurately reflected by manual BP. Automated BP determinations were consistently higher than manual BP, particularly in hypotensive patients. Automated BP devices should not be used for field or hospital triage decisions. Manual BP determinations should be used until systolic blood pressure is consistently > or = 110 mm Hg.


Assuntos
Determinação da Pressão Arterial/métodos , Pressão Sanguínea , Ferimentos e Lesões/classificação , Adulto , Feminino , Humanos , Escala de Gravidade do Ferimento , Modelos Logísticos , Masculino , Oscilometria , Reprodutibilidade dos Testes , Estudos Retrospectivos , Centros de Traumatologia
18.
Arch Surg ; 138(10): 1127-9, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14557131

RESUMO

HYPOTHESIS: The level of cervical spinal cord injury (CSCI) can be used to predict the need for a cardiovascular intervention. DESIGN: Retrospective review. Data included level of spinal cord injury, Injury Severity Score, lowest heart rate, and systolic blood pressure in the first 24 hours and intensive care unit course. The level of CSCI was divided into high (cord level C1-C5) or low (cord level C6-C7). Neurogenic shock was defined as bradycardia with hypotension. Statistical analysis was performed with the t test and the chi2 test. SETTING: Level I trauma center. PATIENTS: The patients studied were those with quadriplegia who experienced a CSCI and were admitted to the hospital between December 1, 1993, and October 31, 2001. INTERVENTIONS: Pressors, chronotropic agents, and pacemakers.Main Outcome Measure Use of a cardiovascular intervention in the presence of neurogenic shock. RESULTS: Eighty-three patients met the criteria for CSCI and quadriplegia, 62 in the high (C1-C5) and 21 in the low (C6-C7) level. There was no significant difference between the 2 groups in mean +/- SD age (38.2+/-17.8 vs 34.7+/-15.6 years; P=.43), mean +/- SD Injury Severity Score (35.7+/-17.5 vs 32.5+/-11.2; P=.44), mean +/- SD admission base deficit (-0.7+/-3.6 vs 0.7+/-2.7; P=.06), or mortality (12 [19%] of 62 patients vs 2 [10%] of 21 patients; P=.29). Neurogenic shock was present in 19 (31%) of the 62 patients with high CSCI and in 5 (24%) of the 21 patients with low CSCI (P=.56). There was a marked difference in the use of a cardiovascular intervention between those with a high and those with a low CSCI: 15 (24%) of 62 patients vs 1 (5%) of 21 patients (P=.02). Two patients with C1 through C5 spinal cord injuries required cardiac pacemakers. CONCLUSIONS: There was no significant difference in the frequency of neurogenic shock by injury level. Patients with a high CSCI (C1-C5) had a significantly greater requirement for a cardiovascular intervention compared with patients with lower injuries (C6-C7).


Assuntos
Bradicardia/fisiopatologia , Bradicardia/terapia , Doenças Cardiovasculares/fisiopatologia , Doenças Cardiovasculares/terapia , Vértebras Cervicais/lesões , Hipotensão/fisiopatologia , Hipotensão/terapia , Traumatismos da Medula Espinal/complicações , Traumatismos da Medula Espinal/fisiopatologia , Adulto , Distribuição de Qui-Quadrado , Feminino , Frequência Cardíaca , Humanos , Escala de Gravidade do Ferimento , Masculino , Quadriplegia/fisiopatologia , Estudos Retrospectivos
19.
J Trauma ; 54(2): 352-5, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12579064

RESUMO

BACKGROUND: Domestic violence (DV) has received increased recognition as a significant mechanism of injury. To improve awareness about DV at our institution, an educational program was presented to the departments of surgery and emergency medicine. Pre and posttests were given and improvement in knowledge was demonstrated. In addition, a screening question for DV was added to the trauma history and physical (H & P) form. This study was done to determine the long-term efficacy of these efforts in increasing recognition of DV and referral to social services in patients admitted to the trauma service. Recognition of DV and appropriate referral should be increased after education and change in H & P form. METHODS: All patients admitted to the trauma service at a Level I trauma center over a 10 month period with the mechanism of injury "assault" were reviewed. DV was determined to be present, likely, unknown, or absent based on information from the prehospital report and medical records. The DV screen question was reviewed for use and accuracy. RESULTS: During the study period, 1,550 patients were admitted to the trauma service, with assault listed as the mechanism of injury for 217 (14%). DV was confirmed or likely in 27 patients (12.4% of the assaults). Of patients with confirmed or likely DV, only 7 received appropriate referrals, with 2 generated by the nursing staff. Of the confirmed and likely DV patients, 17 (63%) were sent home without investigation of safety and only 21% of all assault victims had any social services evaluation (usually to investigate funding or placement). The DV screen was used in only 12 patients. Reasons given for failure to complete the DV screen on the H & P included examiner discomfort in asking the question, and an environment judged to be inappropriate (resuscitation area in the emergency department). CONCLUSION: DV is unrecognized and underreported. Efforts to improve recognition and reporting of DV events need to be ongoing. Screening for DV is not effectively done as part of the initial evaluation. Assessment for DV may be more appropriate as part of the tertiary survey.


Assuntos
Violência Doméstica/estatística & dados numéricos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Serviço Social/estatística & dados numéricos , Centros de Traumatologia/estatística & dados numéricos , Ferimentos e Lesões/etiologia , Adulto , Medicina de Emergência/educação , Feminino , Humanos , Masculino , Prontuários Médicos , Encaminhamento e Consulta , Sistema de Registros , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/psicologia
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