THE IMPACT OF SYSTEMIC DRUGS ON DENTAL IMPLANT OSSEOINTEGRATION: A REVIEW.

The process of osteointegration of dental implants is a biological process. Systemic therapy can interfere with this process, affecting the growth and breakdown processes of the bone and ultimately leading to implant failure. This literature review focuses on specific groups of systemic drugs that directly impact osteointegration. The research in electronic literature was conducted using the National Library of Medicine's PubMed/MEDLINE database from March 2000 to February 2024. The following MeSH (Medical Subject Headings) terms were used: "implant osseointegration," "bisphosphonates," "non-steroidal anti-inflammatory drugs," "glucocorticoids," "proton pump inhibitors," and "selective serotonin reuptake inhibitors (SSRIs)." This search yielded 1,258 articles on implant osseointegration. Among these, 30 articles met our criteria for implant osseointegration and bisphosphonates, 2 articles for non-steroidal anti-inflammatory drugs (NSAIDs), 7 articles for glucocorticoids, 14 articles for proton pump inhibitors (PPIs), and 14 articles for selective serotonin reuptake inhibitors (SSRIs). Clinicians considering implant therapy should be mindful of potential medication-related implant failures. The present systematic review has identified an association between proton pump inhibitors (PPIs), nonsteroidal anti-inflammatory drugs (NSAIDs), selective serotonin reuptake inhibitors (SSRIs), glucocorticoids, and bisphosphonates with an increased implant failure rate.

POSTNATAL CARE AMONG POSTPARTUM WOMEN DURING HOSPITAL DISCHARGE.

The postpartum period is the most important part of the woman's health care, as serious and life-threatening complications can occur during this period. The purpose of this study was to gather information on women's perception regarding postnatal care. The study enrolled 100 postpartum women who attended all the postnatal services at the Obstetrics and Gynecology Clinic in Pristina, Kosovo. Data were collected by a modified questionnaire, which included sociodemographic and clinical characteristics, and women's perception of postnatal care. Frequencies and Chi square were determined using the SPSS software. Most of the respondents (57.0%) belonged to the age group of 31-40 years. The majority of respondents (52.0%) were from rural areas, with secondary school (42.0%), unemployed (62.0%) and middle socio-economic status (91.0%). Of all the postpartum women, 43.0% declared that the gynecological and ultrasonography checkup was done on the second day. A small percentage of women had symptoms of postpartum depression (16.0%), and no difference was found in the level of depression in relation to the mode of delivery. Furthermore, 78.0% of postpartum women were advised to make the next visit on the seventh day after hospital discharge. Uptake of postnatal care services was high. However, implementation of a standardized guideline is required to further advance postnatal care.