Endoscopic Evaluation of Cut Root Faces and Histologic Analysis of Removed Apices Following Root Resection: A Clinical Study.

OBJECTIVE: To evaluate the resection plane after root-end resection during apical surgery using endoscopy. METHODS: Following apicectomy of 69 roots, the cut root faces were inspected with a rigid endoscope for the presence of unfilled areas of the root canal space, gaps between the obturated root canal and dentinal wall, isthmi, 'opaque' dentine and cracks. Endoscopic pictures were captured and assessed using a 12-sectorn transparent grid for determination of location of the studied elements. Furthermore, the removed apices were examined histologically (n=47). The surfaces of the removed apices opposite the cut root faces were histologically analysed for the same outcome measures. RESULTS: Endoscopy revealed the following findings: opaque dentine in 84.1%, unfilled parts of the root canal system in 59.4%, gaps between the existing root canal filling and dentinal walls in 49.3%, and cracks in 10.1% of cases. With regard to isthmi, histology of the removed apices demonstrated an isthmus in two-thirds of those seen with endoscopy at the root end. Ramifications were histologically observed only in 6 root apices. CONCLUSION: The studied elements may cause failure of the root canal treatment, and conventional root canal retreatment or apical surgery may be indicated. The clinical significance of opaque dentine with regard to tooth prognosis after apical surgery remains unclear and warrants further research.

Comparison between Radiographic (2-dimensional and 3-dimensional) and Histologic Findings of Periapical Lesions Treated with Apical Surgery.

INTRODUCTION: The aim of this study was to evaluate the concordance of 2- and 3-dimensional radiography and histopathology in the diagnosis of periapical lesions. METHODS: Patients were consecutively enrolled in this study provided that preoperative periapical radiography (PR) and cone-beam computed tomographic imaging of the tooth to be treated with apical surgery were performed. The periapical lesional tissue was histologically analyzed by 2 blinded examiners. The final histologic diagnosis was compared with the radiographic assessments of 4 blinded observers. The initial study material included 62 teeth in the same number of patients. RESULTS: Four lesions had to be excluded during processing, resulting in a final number of 58 evaluated cases (31 women and 27 men, mean age = 55 years). The final histologic diagnosis of the periapical lesions included 55 granulomas (94.8%) and 3 cysts (5.2%). Histologic analysis of the tissue samples from the apical lesions exhibited an almost perfect agreement between the 2 experienced investigators with an overall agreement of 94.83% (kappa = 0.8011). Radiographic assessment overestimated cysts by 28.4% (cone-beam computed tomographic imaging) and 20.7% (periapical radiography), respectively. Comparing the correlation of the radiographic diagnosis of 4 observers with the final histologic diagnosis, 2-dimensional (kappa = 0.104) and 3-dimensional imaging (kappa = 0.111) provided only minimum agreement. CONCLUSIONS: To establish a final diagnosis of an apical radiolucency, the tissue specimen should be evaluated histologically and specified as a granuloma (with/without epithelium) or a cyst. Analysis of 2-dimensional and 3-dimensional radiographic images alike results only in a tentative diagnosis that should be confirmed with biopsy.

Intraoral hyperplastic Fordyce granule with destruction of bone: a case presentation.

Fordyce granules of the oral mucosa are often discovered during routine dental examinations. They are considered anatomic variations and are typically seen on the labial and buccal mucosa in adults. The present case report describes for the first time in the literature an atypical location of an enlarged Fordyce granule with local bone destruction. The diagnostic process, surgical treatment, and follow-up are presented and discussed.