RESUMO
PURPOSE: We present our experience with surgical management of amiodarone-induced thyrotoxicosis, including preoperative, intraoperative, and postoperative considerations. METHODS: Retrospective review of the medical records and the histological slides and a Medline search of amiodarone and thyroid gland. CONCLUSIONS: Amiodarone is a drug used to treat potentially lethal ventricular arrhythmia. One of the known side effects is thyroid dysfunction. In patients who cannot safely discontinue amiodarone or when medical therapy is ineffective in controlling thyrotoxicosis, thyroidectomy is the treatment of choice.
RESUMO
PURPOSE: Black pigmentation of the thyroid gland is a rare side effect of minocycline. METHODS: Only 26 cases, in addition to the 2 we present, have been reported in the literature. Eleven cases of thyroid carcinoma associated with black thyroid syndrome have been reported. CONCLUSIONS: The incidence of papillary cancer may be increased in thyroid glands stained by the minocycline pigment, which warrants an increased index of suspicion in patients who develop thyroid nodules and have previously been treated with minocycline.