RESUMO
The treatment of diabetic macular edema has known a fast development in the last 5 years where the transition from laser monotherapy to intravitreal pharmacotherapy is becoming standard practice. Intravitreal injections therapy is in a continuous development with promising positive results. The use of intratvitreal devices in the treatment of macular edema of vascular cause has become a viable alternative also in treating diabetic macular edema. Several clinical studies have revealed the superiority of intravitreal treatment versus laser monotherapy. This article is evaluating and reviewing present and future treatments used to combat diabetic macular edema. [corrected].
Assuntos
Glucocorticoides/uso terapêutico , Edema Macular/fisiopatologia , Edema Macular/terapia , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores , Retinopatia Diabética/complicações , Glucocorticoides/administração & dosagem , Humanos , Fotocoagulação a Laser/métodos , Edema Macular/diagnóstico , Edema Macular/etiologia , Ensaios Clínicos Controlados Aleatórios como Assunto , Oclusão da Veia Retiniana/complicações , Resultado do Tratamento , Uveíte Posterior/complicaçõesRESUMO
The paper presents the first results concerning the Aflibercept (Eylea) treatment, the last antiVEGF approved for treatment of the age related macular degeneration (AMD), neovascular form and for macular edema due to the central retinal vein occlusion. The treatment was applied to patients presenting AMD, ME and other diseases: myopic and idiopatic choroidal neovascularisation, central serous choroidopathy (CSC) or diabetic macular edema (DME). The results were good: improvement of the visual acuity, resolution of the intraretinal fluids and macular edema. Although we did not notice major side-effects, resistance or tachyphylaxis, we noticed some recurrences.
Assuntos
Degeneração Macular/tratamento farmacológico , Receptores de Fatores de Crescimento do Endotélio Vascular/uso terapêutico , Proteínas Recombinantes de Fusão/uso terapêutico , Oclusão da Veia Retiniana/tratamento farmacológico , Fator A de Crescimento do Endotélio Vascular/antagonistas & inibidores , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Edema Macular/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
We present a case report of a 56 years old patient with central retinal vein occlusion and macular edema. Intravitreal Ozurdex was effective: the disappearance of the macular edema and improvement of the visual acuity were noticed. Panretinal photocoagulation performed avoided the proliferative retinopathy.
Assuntos
Dexametasona/uso terapêutico , Glucocorticoides/uso terapêutico , Edema Macular/tratamento farmacológico , Edema Macular/cirurgia , Oclusão da Veia Retiniana/tratamento farmacológico , Oclusão da Veia Retiniana/cirurgia , Dexametasona/administração & dosagem , Implantes de Medicamento , Glucocorticoides/administração & dosagem , Humanos , Fotocoagulação , Edema Macular/etiologia , Masculino , Pessoa de Meia-Idade , Oclusão da Veia Retiniana/complicações , Resultado do Tratamento , Acuidade VisualRESUMO
The paper presents retinal imaging (color and red-free photografs, fluorescein angiograms and optical coherence tomography) of the most common hereditary chorioretinal dystrophies: retinitis pigmentosa, Stargardt's disease, choroideremia, cone dystrophy vitteliform dystrophy. Retinal imaging has an important role in the diagnosis and the follow-up of these diseases, but genetic investigations are frequently necessary.
Assuntos
Coroideremia/diagnóstico , Angiofluoresceinografia , Displasia Retiniana/diagnóstico , Tomografia de Coerência Óptica , Coroideremia/genética , Diagnóstico Diferencial , Angiofluoresceinografia/métodos , Humanos , Degeneração Macular/congênito , Degeneração Macular/diagnóstico , Degeneração Macular/genética , Fotografação/instrumentação , Valor Preditivo dos Testes , Displasia Retiniana/genética , Estudos Retrospectivos , Sensibilidade e Especificidade , Doença de Stargardt , Tomografia de Coerência Óptica/métodosRESUMO
PURPOSE: To reveal the etiopathogenic features of the noninfectious uveitis after extracapsular lens extraction, with or without artificial lens implantation. METHOD: A retrospective study including 33 patients with noninfectious uveitis after extracapsular lens extraction with or without artificial lens implantation has been performed. The patients have been selected exclusively according to clinical criteria. RESULT: In 27 patients (80.80%), risk factors for the postoperative uveitis have been identified. Among these, the most frequently incriminated has been the operation itself (14 cases--42.42%), with the persistence of cortical material on the first place: 10 cases (30.30%). CONCLUSION: The unfavourable evolution of the uveitis has been associated with the following risk factors: previous uveitis, the incorrect position of the artificial lens, rheumatoid arthritis, diabetes mellitus.