1.
Bull World Health Organ
; 52(1): 87-90, 1975.
Artigo
em Inglês
| MEDLINE
| ID: mdl-174825
RESUMO
Forty-one children were studied in order to provide information on antibody responses to H. influenzae type b polyribophosphate (PRP), given in combination with diphtheria-pertussis-tetanus vaccine (DPT). When PRP was administered alone, 9 of 15 children demonstrated fourfold or greater increases in titres of anti-PRP antibody. In contrast, in the group receiving a combination vaccine consisting of DPT and PRP only 1 of 13 children showed a similar rise in anti-PRP antibody. It was concluded that, in the population studied, the combination vaccine was less effective than PRP alone. The reasons for this difference and its potential significance are discussed.
Assuntos
Formação de Anticorpos , Vacinas Bacterianas/administração & dosagem , Haemophilus influenzae/imunologia , Bordetella pertussis/imunologia , Pré-Escolar , Toxina Diftérica/administração & dosagem , Feminino , Humanos , Lactente , Masculino , Vacina contra Coqueluche/administração & dosagem , Toxoide Tetânico/administração & dosagem
2.
Bulletin of the World Health Organization (WHO)
; 52(1): 87-90, 1975.
Artigo
em Inglês
| PAHO
| ID: pah-4548