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1.
Glob Pediatr Health ; 7: 2333794X20968676, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33195746

RESUMO

Rising rates of mumps in Georgia have been reported. We hypothesize that the incidence of parotitis and mumps presenting to Children's Healthcare of Atlanta (CHOA) has increased over the past decade among immunized children. Retrospective chart reviews were conducted using ICD9/10-codes for parotitis and mumps from January 2007 to December 2017. Data on demographics, vaccination status, labs, management and disposition were collected. 1017 parotitis cases were diagnosed; an upward trend in incidence occurred over time. Mumps testing was done in 47 (4.6%) parotitis cases; 9 mumps cases were identified, with 6 diagnosed in 2017. Seven patients (78%) were fully vaccinated. Median age for mumps was 13 years. Few symptoms differentiate mumps from non-mumps-parotitis. The incidence of parotitis and mumps in children has increased since 2007 in the Atlanta area, reflecting a nationwide trend. Mumps is likely underreported as rates of testing are low, and should be considered in children with parotitis regardless of vaccination history.

3.
Pediatr Transplant ; 22(8): e13294, 2018 12.
Artigo em Inglês | MEDLINE | ID: mdl-30246483

RESUMO

Necrotizing fasciitis is a life-threatening, rapidly progressing infection of fascia and subcutaneous cellular tissue typically caused by mixed aerobic and anaerobic bacteria. We present a case report of an immunocompromised 4-year-old female with necrotizing fasciitis from a rare fungal organism, Mucor indicus. The patient underwent multiple debridements and was treated for 10 months, first on liposomal amphotericin B (2 months) then posaconazole (8 months). Mucor indicus is a rarely described pathogen with only nine other cases described. Identification of this organism remains a challenge, and the need for further understanding of risk factors and organism susceptibility testing to help guide treatment is crucial.


Assuntos
Transplante de Medula Óssea/efeitos adversos , Fasciite Necrosante/etiologia , Fasciite Necrosante/microbiologia , Mucor , Anfotericina B/uso terapêutico , Pré-Escolar , Desbridamento , Feminino , Humanos , Hospedeiro Imunocomprometido , Imageamento por Ressonância Magnética , Fatores de Risco , Resultado do Tratamento , Triazóis
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