PUBLIC CONFIDENCE IN FORMAL MEDICINE: CURRENT CONTEXT.

OBJECTIVE: The aim: To explore the current context and the main factors of public confidence in formal medicine. PATIENTS AND METHODS: Materials and methods: The article is based on the outcomes of a cross-sectional survey designed to reflect varied dimensions of individual/population' perception of healthcare services, namely: socio-demographic information, reflection on individuals' own health, confidence in healthcare services. A total of 2478 self-referred respondents took part in the survey. RESULTS: Results: The study outcomes evidenced that the vast majority of respondents trusted in formal medicine. High level of public confidence in formal medicine is correlated with the lack of confidence in alternative methods. Amongst the factors influencing formation of public confidence in formal medicine are "satisfaction of basic needs and physical condition of the body", as well as "healthy behavior". It was identified that the most significant influence on the level of public confidence in medicine is made by the individual's satisfaction with the level and quality of physical exertions, satisfaction with the individual's physical condition, and satisfaction with the quality of food. CONCLUSION: Conclusions: The survey outcomes provide the background for outlining specific ways to enhance public confidence in formal medicine, contribute to optimization of funding provided to public health care projects and programs.

[socioecological features of the epidemiology of sarcoidosis in the poltava region, Ukraine].

OBJECTIVE: Introduction: Lung sarcoidosis is a systemic granulomatous disease that can affect various organs and systems of a person. Due to the lack of a uniform standardized approach to the diagnosis of sarcoidosis, the epidemiological pattern is heterogeneous and depends on many factors. The aim: To investigate the correlation between the number of patients with sarcoidosis among the population of the Poltava region (Ukraine) and the ecological characteristics of the industrial activity of the region in comparison with the data on the availability of subspecialists in respiratory diseases. PATIENTS AND METHODS: Materials and methods: The study is based on a retrospective analysis of patients with sarcoidosis living in the Poltava region (Ukraine) for the period from 2008 to 2018. RESULTS: Results: The analysis of the correlation between the intensity of environmental impacts on the region and the number of patients with sarcoidosis did not reveal statistically significant changes. An odds ratio (OR) of the occurrence of sarcoidosis among the urban population has not experienced significant dynamics (OR 1,337, 95% CI: 0.96-1.86) compared with those living in rural areas. The number of specialists performing the duties of a pulmonologist in the region is associated with a significantly higher number of registered patients with various forms of sarcoidosis (r=0.27, p=0.04). CONCLUSION: Conclusions: There was no reliable relationship between the risk of sarcoidosis and habitat in areas with increased ecological and industrial load in the Poltava region. The uneven distribution of specialized medical care reduces the patient's odds of establishing a diagnosis of sarcoidosis in the countryside.

Fibromuscular Dysplasia of the Coronary Arteries: A Case Report and Review of the Literature.

Fibromuscular dysplasia is a nonatherosclerotic and non-inflammatory vascular disease with primary lesion of renal and internal carotid arteries. We present a neonatal case of fibromuscular dysplasia who died on the second day of life. The newborn suffered from fibromuscular dysplasia of the coronary arteries and a congenital heart defect. The interesting feature of this case was the formation of aneurysms of the coronary arteries with pulmonary atresia. This case demonstrates a casuistically rare form of association between fibromuscular dysplasia of the coronary arteries and pulmonary artery atresia.

Impact of endogenous luteinizing hormone serum levels on progesterone elevation on the day of human chorionic gonadotropin administration.

OBJECTIVE: To assess the relationship between endogenous LH serum levels after GnRH analogue administration and serum P elevation on the day of hCG administration (P hCG). DESIGN: Retrospective study. SETTING: Reproductive medicine center in a university hospital. PATIENT(S): A total of 708 patients undergoing a GnRH agonist or antagonist protocol for IVF intracytoplasmic sperm injection. INTERVENTION(S): Controlled ovarian stimulation. MAIN OUTCOME MEASURE(S): Serum P values according to GnRH analogue; correlation between serum LH measurements and P hCG values. RESULT(S): Serum P hCG values were significantly lower following the GnRH antagonist than agonist protocol. A positive correlation between serum P hCG and LH area under the curve or day 6 LH values was found in the GnRH agonist group and between P hCG and LH hCG levels in both GnRH analogue regimens. With multivariate analysis, P hCG values were positively correlated with serum E(2) levels on hCG administration day and with the total FSH dose in both GnRH analogue-treated groups. Additionally, the correlation between serum P hCG and LH hCG values was positive in patients treated with the GnRH agonist protocol. CONCLUSION(S): The lower serum P levels on hCG administration day following the GnRH antagonist protocol are mainly explained by lower granulosa cell steroidogenic activity. The correlation with serum LH hCG values was positive in the GnRH agonist-treated group.