1.
Curr Opin Immunol
; 12(3): 256-66, 2000 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10781404
RESUMO
Adapter molecules contain discrete modular domains that direct specific intermolecular interactions to orchestrate assembly of signaling complexes. A number of adapter proteins play critical roles in both positive and negative regulation of antigen-receptor signaling, influencing lymphocyte development and function.