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1.
Workplace Health Saf ; 68(1): 6-12, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31544630

RESUMO

Background: Addiction and mental health (AMH) professionals often experience high levels of burnout, which can lead to detrimental outcomes for patient care and safety and the AMH professional themselves. Interventions aimed at improving well-being can be useful to tackle the issues surrounding burnout. Specifically, implementing activity-based events (ABEs), which encourages individuals to be more physically active, can be useful in improving physical, mental, and social well-being. Alberta Health Services AMH, Edmonton Zone, implemented a Sports Day event to promote well-being as a way to help offset the risk of burnout. Methods: This was an online anonymous cross-sectional, postsurvey evaluation. The postsurvey was administered to 243 AMH staff and physicians who registered for Sports Day. Findings: The responses from 66 AMH staff and physician attendees indicated that individuals were highly satisfied with the event and felt that Sports Day promoted positive mental and physical well-being, helped to develop a sense of community, and strengthened colleague relationships. Conclusions/Application to Professional Practice: The results build on the literature examining the effects of single-day ABEs and can be implemented by health care organizations to promote staff and physician well-being via increased physical activity. Single-day ABEs, like Sports Day, can promote mental, physical, and social well-being. Organizing a sports day event is a feasible way to help offset the risk of burnout and is generally well received by individuals.


Assuntos
Exercício Físico , Pessoal de Saúde/psicologia , Promoção da Saúde/métodos , Médicos/psicologia , Adulto , Idoso , Alberta , Esgotamento Profissional/prevenção & controle , Estudos Transversais , Feminino , Humanos , Masculino , Saúde Mental , Pessoa de Meia-Idade , Esportes , Inquéritos e Questionários
2.
Schizophr Res ; 77(2-3): 261-70, 2005 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-15890497

RESUMO

Schizophrenia is a chronic, debilitating psychotic illness of unknown etiology that has been the subject of many genetic studies. We studied the neonatal ventral-hippocampal lesioned rat as an animal model of schizophrenia in order to identify novel candidate genes for schizophrenia. Temporal and frontal cortices were assessed using cDNA microarrays for differences in mRNA expression associated with the lesion, haloperidol treatment and in two rat strains with differential sensitivity to the behavioural effects of the lesion. Genes that had altered expression levels as a result of the lesion, that were normalized by haloperidol treatment, and that differed between rat strains were selected. The pattern of differential transcription was confirmed with quantitative PCR for all six candidate genes: large conductance calcium-activated potassium channel, subfamily M, beta member 1 (Kcnmb1); doublecortex (dcx); adenylyl cyclase-associated protein 1 (CAP1); adenosine monophosphate deaminase 2-isoform L (AMPD2); malic enzyme 3, NADP(+)-dependent, mitochondrial (Me3); and aspartylglucosaminidase (AGA). None of these genes has been extensively studied in schizophrenia, and further work with post-mortem tissue and genetic studies are ongoing.


Assuntos
Lobo Frontal/metabolismo , Regulação da Expressão Gênica , RNA Mensageiro/metabolismo , Esquizofrenia/genética , Lobo Temporal/metabolismo , Análise de Variância , Animais , Animais Recém-Nascidos , Modelos Animais de Doenças , Proteína Duplacortina , Lobo Frontal/efeitos dos fármacos , Regulação da Expressão Gênica/efeitos dos fármacos , Haloperidol/farmacologia , Hipocampo/patologia , Masculino , Análise de Sequência com Séries de Oligonucleotídeos , RNA Mensageiro/efeitos dos fármacos , Ratos , Ratos Endogâmicos F344 , Ratos Endogâmicos Lew , Esquizofrenia/metabolismo , Lobo Temporal/efeitos dos fármacos
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