RESUMO
The authors and others have recently demonstrated that veterans with chronic combat-related PTSD (CR-PTSD) have a twofold increased risk of dementia. To understand this increased incidence, they performed a systematic review of the literature on neuroanatomical differences between veterans with chronic CR-PTSD and control subjects (22 included studies). The hippocampus was most commonly and consistently reported to differ between groups, thereby suggesting the hypothesis that PTSD is associated with smaller hippocampi, which increases the risk for dementia. However, an alternate hypothesis is that smaller hippocampal volumes are a preexisting risk factor for PTSD and dementia. Studies are clearly needed to differentiate between these important possibilities.
Assuntos
Hipocampo/patologia , Transtornos de Estresse Pós-Traumáticos/patologia , Estudos de Coortes , Humanos , PubMed/estatística & dados numéricos , Transtornos de Estresse Pós-Traumáticos/epidemiologiaRESUMO
Epidermolytic acanthoma is a rare benign tumor that is characterized by epidermolytic hyperkeratosis on histopathology. Epidermolytic acanthoma usually presents in adulthood as an asymptomatic tumor less than 1 cm in diameter with a verrucous surface. Whereas the lesions can present in either an isolated solitary, localized, or disseminated form, there tends to be a predilection for the genitoscrotal area.
