[Importance of the radioimmune method of determining renin activity in the blood plasma for the differential therapy of hypertension]. / Znachenie radioimmunnogo metoda opredeleniia aktivnosti renina v plazme krovi dlia differentsirovannoi terapii gipertonicheskoi bolezni.

The results of differentiated treatment of patients with hypertensive disease depending on blood plasma renin activity are analyzed. Sixty-seven patients with hypertensive disease and 14 healthy individuals (controls) were examined. Sets of the JCN firm (USA) were used. Persons with high, moderate and low renin activity were distinguished among patients with hypertensive disease. Differentiated therapy was applied depending on the activity of renin: in high renin activity obsidan was given, in low activity drugs of the saluretic group were used. Treatment proved effective in 60 patients (89%). High renin activity is a prognostically unfavourable sign.