[Catalase activity as affected by carnosine and sodium nitrite in vitro]. / Aktyvnist' katalazy za diï nitrytu natriiu ta karnozynu in vitro.

It was shown in vitro that the activity of catalase Penicillium vitale decreases when treated by sodium nitrite to the greater extent than when affected by dipeptide carnosine (beta-alanyl-L-histidine). At alternating introduction of carnosine and NaNO2 that component affected the catalase activity which was the first to be introduced. The entering of the next metabolite into the medium did not change the enzyme activity. It is shown that carnosine binds with a molecule of catalase. Carnosine may be considered one of natural regulators of catalase activity.

[Effect of carnosine on the transformation of sodium nitrite in vitro in the presence of catalase]. / Vplyv karnozynu na peretvorennia nitrytu natriiu in vitro u prisutnosti katalazy.

It was shown that carnosine changes the compacting of ferment's globe. On the one hand, that action is causes with the connecting of haem. On the other hand, carnosine influences on the hydrate's membrane around protein. Dipeptide influences also on the interaction of catalase with sodium nitrite, which intensity depends on sequence of introducing HNO2 and carnosine into the medium.