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1.
Med Phys ; 33(5): 1329-37, 2006 May.
Artigo em Inglês | MEDLINE | ID: mdl-16752568

RESUMO

A CdZnTe detector (CZTD) can be very useful for measuring diagnostic x-ray spectra. The semiconductor detector does, however, exhibit poor hole transport properties and fluorescence generation upon atomic de-excitations. This article describes an analytic model to characterize these two phenomena that occur when a CZTD is exposed to diagnostic x rays. The analytical detector response functions compare well with those obtained via Monte Carlo calculations. The response functions were applied to 50, 80, and 110 kV x-ray spectra. Two 50 kV spectra were measured; one with no filtration and the other with 1.35 mm Al filtration. The unfiltered spectrum was numerically filtered with 1.35 mm of Al in order to see whether the recovered spectrum resembled the filtered spectrum actually measured. A deviation curve was obtained by subtracting one curve from the other on an energy bin by bin basis. The deviation pattern fluctuated around the zero line when corrections were applied to both spectra. Significant deviations from zero towards the lower energies were observed when the uncorrected spectra were used. Beside visual observations, the exposure obtained using the numerically attenuated unfiltered beam was compared to the exposure calculated with the actual filtered beam. The percent differences were 0.8% when corrections were applied and 25% for no corrections. The model can be used to correct diagnostic x-ray spectra measured with a CdZnTe detector.


Assuntos
Algoritmos , Compostos de Cádmio/efeitos da radiação , Modelos Químicos , Radiografia/métodos , Espectrometria por Raios X/métodos , Telúrio/efeitos da radiação , Transdutores , Zinco/efeitos da radiação , Simulação por Computador , Desenho Assistido por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Método de Monte Carlo , Reprodutibilidade dos Testes , Espalhamento de Radiação , Sensibilidade e Especificidade
2.
Med Phys ; 33(4): 959-67, 2006 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16696472

RESUMO

The goal of this work is to develop a technique to measure the x-ray diffraction signals of breast biopsy specimens. A biomedical x-ray diffraction technology capable of measuring such signals may prove to be of diagnostic use to the medical field. Energy dispersive x-ray diffraction measurements coupled with a semianalytical model were used to extract the differential linear scattering coefficients [mus(x)] of breast tissues on absolute scales. The coefficients describe the probabilities of scatter events occuring per unit length of tissue per unit solid angle of detection. They are a function of the momentum transfer argument, x=sin(theta/2)/X, where theta=scatter angle and lambda=incident wavelength. The technique was validated by using a 3 mm diameter 50 kV polychromatic x-ray beam incident on a 5 mm diameter 5 mm thick sample of water. Water was used because good x-ray diffraction data are available in the literature. The scatter profiles from 6 degrees to 15 degrees in increments of 1 degrees were measured with a 3 mm x 3 mm x 2 mm thick cadmium zinc telluride detector. A 2 mm diameter Pb aperture was placed on top of the detector. The target to detector distance was 29 cm and the duration of each measurement was 10 min. Ensemble averages of the results compare well with the gold standard data of A. H. Narten ["X-ray diffraction data on liquid water in the temperature range 4 degrees C-200 degrees C," ORNL Report No. 4578 (1970)]. An average 7.68% difference for which most of the discrepancies can be attributed to the background noise at low angles was obtained. The preliminary measurements of breast tissue are also encouraging.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/fisiopatologia , Mamografia/métodos , Modelos Biológicos , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Difração de Raios X/métodos , Simulação por Computador , Humanos , Transferência Linear de Energia , Modelos Lineares , Imagens de Fantasmas , Doses de Radiação , Radiometria/métodos , Espalhamento de Radiação
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