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Phys Med Biol ; 62(4): 1208-1224, 2017 02 21.
Artigo em Inglês | MEDLINE | ID: mdl-28114116

RESUMO

The use of magnetic resonance (MR) thermometry for the monitoring of thermal ablation is rapidly expanding. However, this technique remains challenging for the monitoring of the treatment of cardiac arrhythmia by radiofrequency ablation due to the heart displacement with respiration and contraction. Recent studies have addressed this problem by compensating in-plane motion in real-time with optical-flow based tracking technique. However, these algorithms are sensitive to local variation of signal intensity on magnitude images associated with tissue heating. In this study, an optical-flow algorithm was combined with a principal component analysis method to reduce the impact of such effects. The proposed method was integrated to a fully automatic cardiac MR thermometry pipeline, compatible with a future clinical workflow. It was evaluated on nine healthy volunteers under free breathing conditions, on a phantom and in vivo on the left ventricle of a sheep. The results showed that local intensity changes in magnitude images had lower impact on motion estimation with the proposed method. Using this strategy, the temperature mapping accuracy was significantly improved.


Assuntos
Ablação por Cateter , Coração/fisiologia , Processamento de Imagem Assistida por Computador/métodos , Imageamento por Ressonância Magnética/métodos , Movimento/fisiologia , Imagem Óptica/métodos , Termometria/métodos , Algoritmos , Animais , Voluntários Saudáveis , Humanos , Imagens de Fantasmas , Análise de Componente Principal , Respiração , Ovinos
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