[Association of metabolic syndrome components with cataract]. / Metabolinio sindromo ir jo komponentu rysys su katarakta.

UNLABELLED: The aim of the study was to evaluate the association of metabolic syndrome and its components with cataract among the middle-aged Kaunas population in relation to gender and age. MATERIAL AND METHODS: The epidemiological examination was carried out in Kaunas, Lithuania, during 2001-2002. Health survey has been carried out according to the protocol of Monitoring of Trends and Determinants in Cardiovascular disease (MONICA) study. Analysis was performed for 1,267 persons aged 35-64 years (571 men and 696 women). Metabolic syndrome was defined by criteria of World Health Organization and The National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). Cataract was defined by color photography according to the Lens Opacities Classification System (LOCS III) methods. RESULTS: After dividing of total cohort into three age groups (35-44, 45-54 and 55-64 years), relationship between metabolic syndrome and cataract was found in 55-64 years old men and 45-54 and 55-64 years old women: the prevalence of cataract was higher in men's and women's groups with metabolic syndrome than in groups of same the age and gender without metabolic syndrome, but significant difference was observed only in women's group. After evaluation of the relationship of every component of metabolic syndrome with cataract it was established that an increased prevalence of cataract was observed among men with hyperglycemia and central obesity and among women with all five components of metabolic syndrome. CONCLUSION: This survey shows that metabolic syndrome was significantly associated with an increased prevalence of cataract in women of Kaunas city population aged 45-64 years.

[Prevalence of cataract in 35-64 years old Kaunas city population]. / Kataraktos paplitimas tarp 35-64 metu Kauno miesto gyventoju

UNLABELLED: The aim of the study was to determine the prevalence of lens opacity among 35-64 years old Kaunas population as well as to evaluate the stage and type of age-related cataract and its distribution in the groups of age and gender. MATERIAL AND METHODS: The material of our study was Kaunas city population aged 35 to 64 years who participated in the scientific Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA-4) study during 2001-2002 in the Laboratory of Population Researches, Institute of Cardiology of Kaunas University of Medicine. During this study random sampling method was used for grouping of 1354 persons according to the age and gender (596 males and 759 females). A total of 2708 lens were examined using the Lens Opacity Classification System (LOCS III) after dilatation of pupils. All the investigated persons were divided into decade age groups: 35-44, 45-54 and 55-64 years. All of them were divided into two groups: with cataract and without. Those who had cataract were divided into three groups according to the three stages of disease. All lenses were divided into seven groups: clear lens, posterior subcapsular, nuclear, cortical and mixed cataract, aphakia and pseudophakia. RESULTS: The lens opacities were present in 106 (17.8%) males and 141 (18.6%) females. The lens opacities of both eyes were observed in 91.3% of investigated persons. In all groups with cataract, the 1st stage comprised 71.6%, 2nd--22.5% and 3rd--6.0% of cases. The prevalence of cataract in decade aged groups according to the stages, respectively in men and women was: among 35-44 years old--1st stage cataract 4.0% and 3.5%, 2nd--unidentified in both groups, 3rd stage--1.0% and unidentified; 45-54 years old--1st stage 9.7% and 9.7%, 2nd--1.0% and 1.1%, 3rd--1.5% and 0.4%; among aged of 55-64 years--the 1st stage as 23.8% and 26.0%, 2nd--9.9% and 11.8%, 3rd--2.0% and 1.5%. In both groups the nuclear cataract dominated (68.2%); in male group--72.4% and female--65.0%. Mixed type comprised 18.3% of cases, respectively 17.9% in males and 18.6% in females, cortical--10.7%, respectively--7.7% and 12.9%; posterior subcapsular--2.8%, respectively--2.8% and 3.4%. CONCLUSIONS: The lens opacities were found in 17.8% of males and 18.6% of females among investigated 35-64 years old population of Kaunas city. In the groups of both genders domination of nuclear cataract and the 1st stage of all forms of cataract was observed. The incidence of cataract increases significantly with age.