[Comparative evaluation of the effectiveness of the treatment of gastroduodenal Campylobacter infection in children]. / Sravnitel'naia otsenka éffektivnosti lecheniia gastroduodenal'nogo kampilobakterioza u detei.

Schemes developed by the authors for antibacterial therapy of gastroduodenal bacterosis caused by Campylobacter spp. in children are described. The data on the treatment of 56 patients with duodenal ulcer and gastroduodenitis are presented. The efficacy of the treatment with medicines under the control of the clinical, endoscopic and microbiological indices was compared. The study showed that De-Nol, furazolidone and combination of trichopol (metronidazole) with vicair were the most efficient drugs for therapy of children with such diseases.

[Isolation of C. pyloridis from children]. / Vydelenie C. pyloridis ot detei.

The authors analyze the findings of gastroduodenal biopsies in 25 children aged 6 to 15 years suffering from mucosal inflammations and functional abnormalities of the upper portions of the digestive tract. Chocolate agar with various bases, one of which has been suggested by the authors, has been used for the isolation of C. pyloridis. Five cultures have been isolated. Microscopic examinations and biochemical identification of the isolates have lead the authors to a conclusion that campylobacter infections of the upper digestive tract may be diagnosed with certainty only after a comprehensive bacteriologic examination.

[Clinico-endoscopic characteristics of gastroduodenal Campylobacter infection in children]. / Kliniko-éndoskopicheskie osobennosti gastroduodena'lnogo kampilo- bakterioza u detei.

During diagnostic esophagogastroduodenoscopy, 104 children aged 6 months to 14 years were subjected to spot biopsy of the mucous membrane of the antral part of the stomach and duodenal bulb with a purpose of subsequent studies for Campylobacter pyloris (C. P.) including primary microscopy, the screening-urease test and culture isolation followed by its identification according to all the necessary biochemical tests. C. P. were detected in 50% of the children examined including 9 out of 12 patients suffering from ulcer disease of the duodenum. It was shown that the C. P. incidence noticeably rose with an increase of the period of the gastroenterologic anamnesis. The characteristic clinical and endoscopic signs of the illness were defined, associated with most or less probable C. P. isolation. It has been established that the findings of the screening-urease test cannot form the basis for the final diagnosis of pyloric campylobacteriosis in children.