Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
Mais filtros










Intervalo de ano de publicação
1.
Rev. Soc. Bras. Med. Trop ; 53: e20190132, 2020. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1057283

RESUMO

Abstract INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel hantavirus and Junin arenavirus antigens for IgG detection by ELISA. RESULTS IgG antibodies to hantavirus and arenavirus were found in 5/506 (1%) and 2/506 (0.4%) serum samples, respectively. CONCLUSIONS: Arenavirus and hantavirus circulate in indigenous populations from the Colombian Caribbean region, and the results indicate that the indigenous populations are exposed to these zoonotic agents, with unknown consequences on their health, despite low seroprevalence.


Assuntos
Humanos , Masculino , Feminino , Adulto , Imunoglobulina G/sangue , Indígenas Sul-Americanos , Orthohantavírus/imunologia , Arenavirus/imunologia , Infecções por Arenaviridae/epidemiologia , Infecções por Hantavirus/epidemiologia , Anticorpos Antivirais/sangue , Ensaio de Imunoadsorção Enzimática , Estudos Soroepidemiológicos , Estudos Transversais , Fatores de Risco , Colômbia/epidemiologia , Infecções por Arenaviridae/diagnóstico , Infecções por Hantavirus/diagnóstico
2.
Rev Soc Bras Med Trop ; 53: e20190132, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31859943

RESUMO

INTRODUCTION: In Colombia, there is insufficient epidemiological surveillance of zoonotic hemorrhagic viruses. METHODS: We performed a sero-epidemiological study in indigenous populations of Wayuü, Kankuamos, and Tuchin communities using Maciel hantavirus and Junin arenavirus antigens for IgG detection by ELISA. RESULTS: IgG antibodies to hantavirus and arenavirus were found in 5/506 (1%) and 2/506 (0.4%) serum samples, respectively. CONCLUSIONS: Arenavirus and hantavirus circulate in indigenous populations from the Colombian Caribbean region, and the results indicate that the indigenous populations are exposed to these zoonotic agents, with unknown consequences on their health, despite low seroprevalence.


Assuntos
Anticorpos Antivirais/sangue , Infecções por Arenaviridae/epidemiologia , Arenavirus/imunologia , Infecções por Hantavirus/epidemiologia , Imunoglobulina G/sangue , Indígenas Sul-Americanos , Orthohantavírus/imunologia , Adulto , Infecções por Arenaviridae/diagnóstico , Colômbia/epidemiologia , Estudos Transversais , Ensaio de Imunoadsorção Enzimática , Feminino , Infecções por Hantavirus/diagnóstico , Humanos , Masculino , Fatores de Risco , Estudos Soroepidemiológicos
3.
J Infect Dev Ctries ; 9(10): 1126-32, 2015 Oct 29.
Artigo em Inglês | MEDLINE | ID: mdl-26517488

RESUMO

INTRODUCTION: The Caribbean area of Colombia has been severely affected by a Chikungunya virus (CHIKV) outbreak since 2014. METHODOLOGY: The study was carried out on 100 patients during a fever outbreak from August to September 2014 in two small rural villages in the northern Caribbean area of Colombia. The molecular assays performed by reverse transcription polymerase chain reaction (RT-PCR) on acute patient sera were collected within one to five days of the appearance of symptoms. Sequence analyses were carried out based on phylogenetic analyses of genes NS1 and E2. For serological assays, 49 (49%) patients at ≥ 6 days of disease onset were tested with NovaLisa Chikungunya IgG/IgM µ-capture enzyme-linked immunosorbent assay (ELISA). RESULTS: The main signs or symptoms associated with Chikungunya infection were arthralgia of the lower limbs (96%), fever (91%), arthralgia of the upper limbs (85%), rash (64%), and headache (57%). Ninety-four percent (46/49) of patients were positive for either IgM or IgG; the remaining three (6%) patients were seronegative. Viral loads were detected in 25 patients. Based on phylogenetic analysis of NS1 and E2, the characterization of the Colombian CHIKV indicated that it was a strain closely related to the British Virgin Islands strain and to the Asian genotype. CONCLUSIONS: This study shows the phylogenetic and clinical description of CHIKV in Colombia. The main symptoms shown were: arthralgia, fever, and rash. CHIKV sequences detected in Colombian patients were within the Asian genotype and closely related to the British Virgin Islands strain.


Assuntos
Febre de Chikungunya/epidemiologia , Febre de Chikungunya/patologia , Vírus Chikungunya/classificação , Vírus Chikungunya/isolamento & purificação , Surtos de Doenças , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Anticorpos Antivirais/sangue , Região do Caribe/epidemiologia , Vírus Chikungunya/genética , Criança , Colômbia/epidemiologia , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , Pessoa de Meia-Idade , Filogenia , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Análise de Sequência de DNA , Homologia de Sequência , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...