RESUMO
Measles, mumps, and rubella are viral diseases that may adversely affect nonimmune pregnant women and their fetuses/neonates. Prevention of these diseases and their complications can be achieved through measles-mumps-rubella (MMR) vaccination before pregnancy. The vaccine is contraindicated during pregnancy, because it contains live, attenuated viruses that pose a theoretical risk to the fetus. However, accidental receipt of MMR vaccination is not known to cause maternal/fetal complications. MMR immunization is recommended to nonimmune obstetric patients upon completion or termination of pregnancy.
Assuntos
Vacina contra Sarampo-Caxumba-Rubéola/administração & dosagem , Sarampo/prevenção & controle , Caxumba/prevenção & controle , Complicações Infecciosas na Gravidez/prevenção & controle , Rubéola (Sarampo Alemão)/prevenção & controle , Contraindicações , Feminino , Promoção da Saúde , Humanos , Imunoglobulinas/uso terapêutico , Fatores Imunológicos/uso terapêutico , Transmissão Vertical de Doenças Infecciosas/prevenção & controle , Sarampo/complicações , Sarampo/diagnóstico , Sarampo/tratamento farmacológico , Sarampo/epidemiologia , Caxumba/complicações , Caxumba/diagnóstico , Caxumba/epidemiologia , Gravidez , Complicações Infecciosas na Gravidez/etiologia , Rubéola (Sarampo Alemão)/diagnóstico , Rubéola (Sarampo Alemão)/epidemiologia , Populações VulneráveisRESUMO
The results for a real-time PCR assay, using the LightCycler Strep B analyte-specific reagents (Roche Diagnostics Corporation, Indianapolis, Ind.), were compared to a direct plate method combined with a broth enrichment culture method for detection of group B streptococcus colonization in pregnant women. Two separate evaluations were conducted using two different automated nucleic extraction instruments, the MagNA Pure LC instrument (Roche Diagnostics Corporation) and the lower-capacity MagNA Pure Compact instrument (Roche Diagnostics Corporation). The sensitivities, specificities, and positive and negative predictive values for the different evaluation methods were as follow: for the LightCycler Strep B assay with MagNA Pure LC, 100, 97, 90, and 100%, respectively; for the LightCycler Strep B assay with MagNA Pure Compact, 92.5, 99, 97, and 97.5%, respectively. The LightCycler Strep B assay combined with either MagNA Pure LC or MagNA Pure Compact extraction is a suitable method for detecting group B streptococcus colonization in pregnant women. An advantage of the LightCycler assay over culture is the considerably reduced turnaround time for results.
Assuntos
Portador Sadio/diagnóstico , Reação em Cadeia da Polimerase/métodos , Reto/microbiologia , Streptococcus agalactiae/isolamento & purificação , Vagina/microbiologia , Feminino , Humanos , Gravidez , Sensibilidade e Especificidade , Fatores de TempoRESUMO
BACKGROUND: Urethral prolapse is frequently encountered in girls. Although its occurrence in elderly women is not rare, little published information exists regarding this clinical condition or its management. CASE: A 90-year-old woman (gravida 1, para 1) with a four-year history of intermittent vaginal bleeding had both urethral and uterovaginal prolapse. The condition was initially managed conservatively with estrogen and a pessary. Ultimately, surgical intervention was required for complete resolution. CONCLUSION: Urethral prolapse can occur in elderly women and may present concomitantly with other forms of pelvic floor dysfunction such as uterovaginal prolapse. Conservative treatment with estrogen is partially effective in reducing the size of the urethral prolapse and may point to hypoestrogenism as one potential cause of this condition in elderly women. However, surgical management may ultimately be required for complete resolution of these problems, even in medically compromised patients.
