[Central hemodynamics of dogs in the early postresuscitation period and the outcome of resuscitation]. / Nekotorye pokazateli tsentral'noi gemodinamiki u sobak v rannem postreanimatsionnom periode i iskhod ozhivleniia.

Variations in central hemodynamics of dogs were compared with the outcome of resuscitation of 18 dogs subjected to 12-minute reversible circulatory arrest because of ventricular fibrillation. Nine survived dogs with completely recovered neurological status during the first 10 minutes after resuscitation had moderate hypertension, the mean arterial pressure (MAP) being 175.0 + 8.9 mm Hg. In the dogs who died within 24-48 hours after resuscitation, the MAP did not rise during this period as compared to the initial level; 2 dogs developed excessive hypertension (MAP about 200 mm Hg). There were also found certain differences in other parameters of central hemodynamics. Moderate hypertension in the first 10 minutes of the postresuscitation period leads to rapid restoration of the adequate level of peripheral blood flow in organs and tissues, thus favouring survival of animals subjected to a long circulatory arrest.

[Interrelationship of changes in central hemodynamics in the postresucitation period with development of posthypoxic cerebral edema]. / Vzaimosviaz' izmenenii tsentral'noi gemodinamiki v postreanimatsionnom periode s razvitiem postgipoksicheskogo oteka mozga

A syndrome of low cardiac output developed between the 1st and the 3rd hours after the resuscitation in 16 dogs after the arrest of blood circulation for 15 minutes. The increase of cardiac output at the initial period of resuscitation took place in 50% of cases before the development of this syndrome. In the absence of hyperperfusion at the beginning of the resuscitation the animals died 9 to 23 hours after the experiment. Cerebral cortex edema developed in all the survived dogs which had low cardiac output 24 hours after resuscitation, but it was not observed in animals with high cardiac output.