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G Ital Med Lav Ergon ; 29(3 Suppl): 534-6, 2007.
Artigo em Italiano | MEDLINE | ID: mdl-18409817

RESUMO

Mercury (Hg) exposure makes happen disease to humans and animals spreading in all body compartments, especially in liver and kidney. In these ones, copper, zinc, manganese and iron were investigated to assess perturbation of essential metals' homeostasis due to Hg chronic intoxication. Because L-arginine, is able to induce beneficial influence on immunologic functions on mice intoxicated with Hg, we also studied the efficiency of detoxification process before and after treatment with this aminoacid. Adding L-arginine to diet of the intoxicated mice we achieved a good restoration to normal homeostatic conditions.


Assuntos
Arginina/uso terapêutico , Inativação Metabólica , Rim/efeitos dos fármacos , Rim/metabolismo , Fígado/efeitos dos fármacos , Fígado/metabolismo , Mercúrio/toxicidade , Animais , Camundongos , Camundongos Endogâmicos BALB C
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