1.
Res Commun Chem Pathol Pharmacol
; 22(3): 455-64, 1978 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-734225
RESUMO
A carbon-13 nuclear magnetic resonance comparison of synthetic and biological samples was used to identify unequivocally 2-hydroxy-3-O-methyl-6beta-naltrexol as a minor naltrexone metabolite in humans. This study points up the increasing usefulness of natural abundance carbon-13 nuclear magnetic resonance techniques in metabolism studies.