Puente miocárdico evaluado mediante tomografía computarizada multidetectores: posible causa del dolor torácico en pacientes más jóvenes con baja prevalencia de dislipemia / Myocardial bridging assessed by multidetector computed tomography: likely cause of chest pain in younger patients with low prevalence of dyslipidemia

Introducción y objetivos. La relación entre los puentes miocárdicos y el dolor torácico todavía no está bien definida. El objetivo de nuestro estudio es evaluar la relación entre los puentes miocárdicos detectados mediante tomografía computarizada multidetectores y los síntomas de una población de pacientes evaluados por dolor torácico. Métodos. Se incluyó a 393 pacientes consecutivos sin enfermedad coronaria previa, estudiados por dolor torácico y remitidos para tomografía computarizada multidetectores entre enero de 2007 y diciembre de 2010. Se les realizó una coronariografía no invasiva mediante tomografía computarizada multidetectores. Se definió puente miocárdico como una parte de una arteria coronaria completamente rodeada por el miocardio en las imágenes axiales y las reconstrucciones multiplanares. Resultados. La media de edad fue 64,6±12,4 años; el 44,8% de los pacientes eran varones. La tomografía computarizada multidetectores mostró 86 puentes miocárdicos en 82 de los 393 pacientes (20,9%). La descendente anterior izquierda fue la arteria coronaria afectada con mayor frecuencia (87,2%). La prevalencia de puente miocárdico fue significativamente superior entre los pacientes sin estenosis coronaria aterosclerótica significativa según la tomografía computarizada multidetectores (el 24,9 frente al 15,0%; p=0,02). Los pacientes con puente miocárdico eran más jóvenes (60,3±13,8 frente a 65,8±11,9 años; p < 0,001), tenían menor prevalencia de hiperlipemia (el 29,3 frente al 41,8%; p=0,03) y mayor prevalencia de miocardiopatía (el 6,1 frente al 1,6%; p=0,02) que los pacientes sin puente miocárdico observado en la tomografía computarizada multidetectores. Conclusiones. La tomografía computarizada multidetectores es una herramienta fácil y fiable para diagnosticar los puentes miocárdicos in vivo. Los resultados del presente estudio indican que los puentes miocárdicos son la causa del dolor torácico en un subgrupo de pacientes más jóvenes, con menor prevalencia de hiperlipemia y mayor prevalencia de miocardiopatía que los pacientes en que se observa ateroesclerosis coronaria significativa en la tomografía computarizada multidetectores (AU)

Introduction and objectives. The relationship between myocardial bridging and symptoms is still unclear. The purpose of our study was to assess the relationship between myocardial bridging detected by multidetector computed tomography and symptoms in a patient population with chest pain syndrome. Methods. The study enrolled 393 consecutive patients without previous coronary artery disease studied for chest pain and referred to multidetector computed tomography between January 2007 and December 2010. Noninvasive coronary angiography was performed using multidetector computed tomography. Myocardial bridging was defined as part of a coronary artery completely surrounded by myocardium on axial and multiplanar reformatted images. Results. Mean age was 64.6 (12.4) years and 44.8% were male. Multidetector computed tomography detected 86 myocardial bridging images in 82 of the 393 patients (20.9%). Left anterior descending was the most frequent coronary artery involved (87.2%). The prevalence of myocardial bridging was significantly higher in patients without significant atherosclerotic coronary stenosis on multidetector computed tomography (24.9% vs 15.0%; P=.02). Patients with myocardial bridging were younger (60.3 [13.8] vs 65.8 [11.9]; P<.001), had less prevalence of hyperlipidemia (29.3% vs 41.8%; P=.03), and more prevalence of cardiomyopathy (6.1% vs 1.6%; P=.02) compared with patients without myocardial bridging on multidetector computed tomography. Conclusions. Multidetector computed tomography is an easy and reliable tool for comprehensive in vivo diagnosis of myocardial bridging. The results of the present study suggest myocardial bridging is the cause of chest pain in a subgroup of younger aged patients with less prevalence of hyperlipidemia and more prevalence of cardiomyopathy than patients with significant atherosclerotic coronary artery disease on multidetector computed tomography (AU)

Myocardial bridging assessed by multidetector computed tomography: likely cause of chest pain in younger patients with low prevalence of dyslipidemia.

INTRODUCTION AND OBJECTIVES: The relationship between myocardial bridging and symptoms is still unclear. The purpose of our study was to assess the relationship between myocardial bridging detected by multidetector computed tomography and symptoms in a patient population with chest pain syndrome. METHODS: The study enrolled 393 consecutive patients without previous coronary artery disease studied for chest pain and referred to multidetector computed tomography between January 2007 and December 2010. Noninvasive coronary angiography was performed using multidetector computed tomography. Myocardial bridging was defined as part of a coronary artery completely surrounded by myocardium on axial and multiplanar reformatted images. RESULTS: Mean age was 64.6 (12.4) years and 44.8% were male. Multidetector computed tomography detected 86 myocardial bridging images in 82 of the 393 patients (20.9%). Left anterior descending was the most frequent coronary artery involved (87.2%). The prevalence of myocardial bridging was significantly higher in patients without significant atherosclerotic coronary stenosis on multidetector computed tomography (24.9% vs 15.0%; P=.02). Patients with myocardial bridging were younger (60.3 [13.8] vs 65.8 [11.9]; P<.001), had less prevalence of hyperlipidemia (29.3% vs 41.8%; P=.03), and more prevalence of cardiomyopathy (6.1% vs 1.6%, P=.02) compared with patients without myocardial bridging on multidetector computed tomography. CONCLUSIONS: Multidetector computed tomography is an easy and reliable tool for comprehensive in vivo diagnosis of myocardial bridging. The results of the present study suggest myocardial bridging is the cause of chest pain in a subgroup of younger aged patients with less prevalence of hyperlipidemia and more prevalence of cardiomyopathy than patients with significant atherosclerotic coronary artery disease on multidetector computed tomography. Full English text available from:www.revespcardiol.org.

Mild heart failure is a mortality marker after a non-ST-segment acute myocardial infarction.

BACKGROUND: The Killip classification categorizes heart failure (HF) in acute myocardial infarction, and has a prognostic value. Although non-ST-elevation myocardial infarction (NSTEMI) is increasing steadily, little information is available about the prognostic value of low Killip class in this scenario. Our aim was to assess the prognostic value of mild HF in NSTEMI. METHODS: 835 patients with NSTEMI between 2005 and 2007 were prospectively recruited. Patients in Killip-1 (K1=684) or Killip-2 class (K2=113) were selected (38, with K>2, excluded). Clinical, angiographic, treatment strategies, and 30-day all-cause mortality, together with other cardiovascular outcomes were recorded. RESULTS: K2 patients were mostly women (K1 27.9% vs K2 48.0%, p<0.001) and older (K1 66.6years vs K2 73.8years, p<0.001) with a higher frequency of diabetes mellitus (p<0.001) and hypertension (p<0.001). Smoking was less frequent in the K2-group (p=0.003). A previous infarction/revascularization history was similar in both groups. The infarction size, assessed by Troponin I/Creatin kinase, did not differ between groups (p=0.378 and p=0.855). Multivessel coronary disease and revascularization procedures were less common in group K2 (p=0.015 and p=0.005 vs group K1, respectively). Patients in K2 had a worse prognosis in terms of maximum Killip class, death and major adverse cardiovascular events (p<0.001). After multivariate analysis, mild HF at presentation was an independent risk factor for mortality (OR=6.50; IC 95%: 2.48-16.95; p<0.001). CONCLUSION: Mild HF at presentation in NSTEMI is linked to a poor prognosis, with increased short-term mortality. Thus, a more aggressive approach including early cardiac catheterization and revascularization should be considered.