[Treatment of septicopyemic forms of acute hematogenic osteomyelitis using dimexide and hyperbaric oxygenation]. / Lechenie septikopiemicheskikh form ostrogo gematogennogo osteomielita u detei s primeneniem dimeksida i giperbaricheskoi oksigenatsii.

Dimexide and HBO-therapy were included in the curative complex for 54 patients with septicopyemic forms of acute hematogenic osteomyelitis, The authors' recommendations proved to be effective which was demonstrated by better general state of the children, less edema of tissues, stimulation of reparative processes of the osseous tissue in the injury zone, normalization of general and biochemical indices of blood.

[Comprehensive treatment of acute hematogenic osteomyelitis in newborn and young infants by using dimexide and HBO therapy]. / Kompleksnoe lechenie ostrogo gematogennogo osteomielita novorozhdennykh i detei rannego vozrasta s primeneniem dimeksida i GBO-terapii.

Dimexid and HBO-therapy were used in the complex treatment of 129 newborns and infants with epiphysial and metaepiphysial osteomyelitis. The use of HBO-therapy and dimexid in the complex treatment of acute hematogenic osteomyelitis gave positive therapeutic effect in all the patients. The general condition improved, blood indices both general and biochemical became normal. X-ray analysis showed less destruction and more rapid reparative processes in the bones.

[Use of hyperbaric oxygenation and dimexide (DMSO) in the overall treatment of chronic hematogenic osteomyelitis in children]. / Primenenie giperbaricheskoi oksigenatsii i dimeksida (DMSO) v kompleksnom lechenii khronicheskogo gematogennogo osteomielita u detei.

It has been shown that the use of hyperbaric oxigenation and dimexide for the treatment of chronic osteomyelitis in 43 children had positive therapeutic effect in all the patients. The general state of the patient improved, both general and biochemical properties became normal sooner. Radiological data have shown the reparative processes in the bone tissue to become more rapid.

[Treatment of experimental osteomyelitis with dimexid, protease inhibitors and proteolytic enzymes]. / Lechenie éksperimental'nogo osteomielita dimeksidom, ingibitorami proteaz i proteoliticheskimi fermentami.

Acute osteomyelitis of the tibial bone was induced in 100 young rabbits. Four series of experiments were conducted. Treatment of osteomyelitis began from the 15th day after challenge. Antibiotics were used for the treatment of all the animals. The best results were obtained in the series where rabbits were injected dimexid intraosseously in addition to antibiotics. Unsatisfactory results were obtained in the series where the animals were given tripsin in addition to antibiotics. In 14 rabbits extensive phlegmonas developed and 8 rabbits died. Roentgenograms revealed extensive destruction of bones.

[Hyperbaric oxygen therapy and dimexide in the overall treatment of osteomyelitis in children]. / Giperbaricheskaia oksigenoterapiia i dimeksid v kompleksnom lechenii osteomielita u detei.

In the complex treatment of 25 children with acute osteomyelitis and 7 children with aggravation of chronic osteomyelitis HBO-therapy and dimexide wwere used. This treatment produced a favourable therapeutic effect in all the patients. X-ray investigation proved the decrease of bony destructions and acceleration of reparative process in the bones.

[Use of dimexide in the treatment of acute hematogenic osteomyelitis in children]. / Primenenie dimeksida pri lechenii ostrogo gematogennogo odteomielita u detei

Under observation were 132 children with acute hematogenous osteomyelitis. The complex treatment of an acute stage of hematogenic osteomyelitis included also the local use of 33% dimexide (DMSO) solution together with antibiotics. The observations indicated a high efficacy of the suggested therapeutic method.