1.
Clin Biochem
; 42(15): 1565-7, 2009 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19615986
RESUMO
OBJECTIVES: To compare N-acetyl-beta-hexosaminidase (HEX) activity in the serum and urine of smokers as well as non-smokers with renal cancer, and healthy people. DESIGN AND METHODS: To assess hexosaminidase activity the level of p-nitrophenol released from p-nitrophenol derivatives was measured. RESULTS: The activity of enzyme was significantly higher in cancer group, with the highest activity in non-smokers. CONCLUSIONS: Cigarette smoking can inhibit, by the influence on HEX activity, catabolism of oligosaccharide chains in cancer tissues.