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1.
Biomed Mater Eng ; 26 Suppl 1: S477-86, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26406039

RESUMO

Optimal graft design has been an objective of many researchers to find correlations between hemodynamics and graft failure. Compared to planar grafts, the helical graft configurations improve hemodynamic performance including the promotion of flow mixing and reduction of flow stagnation regions. In order to evaluate the advantages and disadvantages of the suggested helical type bypass graft model in comparison to a conventional bypass graft configuration, three experimental models were designed and evaluated. The character of complex vortex structures created in the area between the heel and the occluded section depends on the flow parameters (in the case of the straight graft). We have identified two vortices in the symmetrical plane (proximal and distal to the anastomosis). In the new design of the two-turn helical graft, the stagnation point is eliminated from the anastomoses at different time intervals compared to the conventional straight bypass model The present study indicated that the magnitude of the pressure drop along a helical graft was considerably increased compared to a traditional graft which, while still physiologically advantageous, can be surpassed by an optimal geometry model.


Assuntos
Prótese Vascular , Ponte de Artéria Coronária/instrumentação , Ponte de Artéria Coronária/métodos , Vasos Coronários/fisiopatologia , Vasos Coronários/cirurgia , Modelos Cardiovasculares , Velocidade do Fluxo Sanguíneo , Pressão Sanguínea , Simulação por Computador , Circulação Coronária , Análise de Falha de Equipamento , Humanos , Desenho de Prótese , Resultado do Tratamento
2.
Biomed Mater Eng ; 24(1): 853-60, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24211972

RESUMO

The long-term success of arterial bypass surgery is often limited by the progression of intimal hyperplasia at the anastomosis between the graft and the native artery. The experimental models were manufactured from glass tubing with constant internal diameter of 8 mm, fashioned into a straight configuration and helical configuration. The aim of this study was to determine the three-dimensional flow structures that occur at the proximal anastomosis under pulsatile flow conditions, to investigate the changes that resulted from variations in the anastomosis angle and flow division, and to establishing the major differences between the straight and helical graft. In the anastomosis domain, a strong region of recirculation is observed near the occluded end of the artery, which forces the flow to move into the perfused host coronary artery. The proximal portion of the host tube shows weak counter-rotating vortices on the symmetry plane. The exact locations and strengths of the vortices in this region are only weakly dependent on Re. A detailed comparison of experimentally measured axial velocity patterns for straight and helical grafts confirm the very strong nature of the secondary flows in the helical geometry. The helical configuration promotes the mixing effect of vortex motion such that the flow particles are mixed into the blood stream disal to the anastomotic junction.


Assuntos
Anastomose Cirúrgica/métodos , Prótese Vascular , Ponte de Artéria Coronária/métodos , Reologia , Coagulação Sanguínea , Velocidade do Fluxo Sanguíneo , Simulação por Computador , Vasos Coronários/patologia , Vasos Coronários/cirurgia , Desenho de Equipamento , Vidro , Hemodinâmica , Humanos , Hidrodinâmica , Modelos Cardiovasculares , Fluxo Pulsátil , Resistência ao Cisalhamento , Túnica Íntima/patologia , Enxerto Vascular/métodos
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