PANACEA resilient and secure toolkit for healthcare infrastructures.

Healthcare organizations are frequently subject to cybersecurity incidents. The outbreak of a pandemic such as COVID-19 has shown the need for specific operational and organizational measures to be in place in order to reduce the risk of successful cyberattacks. Time will be key: preparation is needed to ensure quick secure set-up of additional resources (IT, staff, medical devices) when the next emergency will hit. The PANACEA Solution Toolkit is a suite of complementary tools to provide Health Care Organizations (HCO) with assessment, guidance, technical and organizational "infrastructure" to address the cybersecurity challenges. It provides support for fortifying health organizations against cyber threats on multiple different levels (technical, behavioral, organizational, strategical) and across a diverse set of workflows and scenarios. In order to determine whether the toolkit satisfies the specific business and users' requirements in the selected use cases, a detailed validation plan and execution roadmap is established taking into account the constraints of the current emergent situation.

Aging Does Not Affect Beta Modulation during Reaching Movements.

During movement, modulation of beta power occurs over the sensorimotor areas, with a decrease just before its start (event-related desynchronization, ERD) and a rebound after its end (event-related synchronization, ERS). We have recently found that the depth of ERD-to-ERS modulation increases during practice in a reaching task and the following day decreases to baseline levels. Importantly, the magnitude of the beta modulation increase during practice is highly correlated with the retention of motor skill tested the following day. Together with other evidence, this suggests that the increase of practice-related modulation depth may be the expression of sensorimotor cortex's plasticity. Here, we determine whether the practice-related increase of beta modulation depth is equally present in a group of younger and a group of older subjects during the performance of a 30-minute block of reaching movements. We focused our analyses on two regions of interest (ROIs): the left sensorimotor and the frontal region. Performance indices were significantly different in the two groups, with the movements of older subjects being slower and less accurate. Importantly, both groups presented a similar increase of the practice-related beta modulation depth in both ROIs in the course of the task. Peak latency analysis revealed a progressive delay of the ERS peak that correlated with the total movement time. Altogether, these findings support the notion that the depth of beta modulation in a reaching movement task does not depend on age and confirm previous findings that only ERS peak latency but not ERS magnitude is related to performance indices.