[Implementation, of multidisciplinary consultations for patients with inflammatory arthritis and treated with subcutaneous biologic DMARDs: Assessment at one year and outlook]. / Mise en place de consultations pluridisciplinaires pour des patients atteints de rhumatisme inflammatoire chronique et traités par biothérapie sous-cutanée : bilan à un an et perspectives.

INTRODUCTION: Biologics (bDMARDs) have revolutionized the prognosis of patients with inflammatory arthritis, but are not without serious side effects. The patient must be able to identify them, acquire self-care abilities or skills and adhere to their treatment. Multidisciplinary consultations, including a pharmaceutical consultation could improve the care of these patients. The pharmaceutical presence make it easier to switch to a biosimilar with etended patient support thanks to the community-hospital network. The return on investment is possible thanks to the more frequent use of biosimilars and the pricing of this type of consultation by the "Forfait de Prestation Intermédiaire". METHODOLOGY: Eligible patients are patients with rheumatoid arthritis or spondyloarthritis, treated with subcutaneous bDMARDs. The criteria assessed were patient's knowledge of their biotherapy using the Biosecure score, their medication adherence using the CQR-5, the total of switch to biosimilars perform and the financial statement of the consultations. An assessment of the actions deployed for the community-hospital network. RESULTS: Two hundred and ninety-five patients (47.4%) benefited multidisciplinary consultation. The mean score of the Biosecure score was 69.6/100 (moderate knowledge) and 261 patients (88.5%) were highly adherent. 57 patients (73%) accepted the switch to biosimilar. 197 pharmacy were contacted, all of witch for patients who receive the switch. Overall patient's satisfaction was 26.9/28. CONCLUSION: Multidisciplinary consultations with involvement of the pharmacist should optimized patient care and the management of outpatients treated with bDMARDs. Patients have already expressed their satisfaction with this course of care and the return on investment is positive.

[Improvement of knowledge of patients treated with an oral anticoagulant after a pharmaceutical interview at the hospital]. / Amélioration des connaissances des patients traités par un anticoagulant oral après avoir bénéficié d'un entretien pharmaceutique à l'hôpital.

OBJECTIVES: Patients treated with oral anticoagulants need an adapted education in order to optimize the management of these treatments. The objective was to assess the knowledge of patients before and after a pharmaceutical interview carried out by pharmacy students on digital tablets at the hospital. METHODS: A prospective study took place in the cardiology department, with a first phase from December 2016 to June 2018. Patient's knowledge were assessed during a pharmaceutical interview; additional informations were done for unacquired concepts. The second phase took place in October 2018, and patient's knowledge were assessed during a phone call for patients who had at least given one wrong answer on the four selected questions. RESULTS: Sixty-eight and twenty-two patients were included respectively for phases 1 and 2 (mean age=70±3.4; treatments number=8.2±0.9). 36 patients were treated by Vitamin K antagonists and 32 by direct oral anticoagulants. 57% of patients with oral anticoagulants gave a good answer for principles of the treatment and the surveillance during phase 1, and 33% for signs of overdose. A significant improvement for the 22 patients with poor knowledge was observed in phase 2 (1.73 vs. 2.5; P=0.006). CONCLUSIONS: The playful interview improves the patient's knowledge over time. Developing the relationship between the hospital and community pharmacists would allow us to optimize the patient follow-up.