1.
Bioorg Med Chem Lett
; 21(5): 1493-7, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21282057
RESUMO
A new class of anti-biofilm compounds possessing 1,4-disubstituted-(1H)-1,2,3-triazolic cores was designed. Their efficient synthesis was performed by means of click chemistry through 1,3-dipolar cycloadditions. Two compounds were found to act as specific anti-biofilm agents against a gram negative species.