RESUMO
2-(Diethylphosphonate)-nitrosopropane (DEPNP), prepared by oxidation of the corresponding aminophosphonate, was found to essentially exist as monomer in both water and organic solvents. The mechanisms of its degradation under 80 degrees C heating or visible light exposure were studied by EPR spectroscopy: its decomposition gave rise to paramagnetic by-products, which have been identified as DEPNP/.C(CH(3) )(2) [P(O)(OC(2) H(5) )(2) ] and DEPNP/.P(O)(OC(2) H(5) )(2) spin adducts. Despite this drawback, DEPNP was successfully used as spin trapping agents to scavenge various carbon - and phosphorus-centred free radicals both in aqueous and organic media, giving rise to intense EPR spectra characteristic of the species trapped.
Assuntos
Compostos Nitrosos/química , Organofosfonatos/química , Espectroscopia de Ressonância de Spin Eletrônica , Detecção de SpinRESUMO
The authors describe one case of calcified lipogranuloma observed in the forearm tissues of a 67 year old patient. This lesion seems to be due to a long term treatment by S.C injection of gomenoleo oil 60 years before. The analysis by high performance liquid chromatography of fat parts of the lesion identified the original olive oil (excipient).