Primary hepatic origin of a neuroendocrine tumor: A rare case report.

Introduction: Neuroendocrine tumors are mainly located in gastrointestinal tract, pancreas and lungs. The primary hepatic origin of neuroendocrine tumors is extremely rare. Case presentation: A 57-year-old female with a history of cholecystectomy presented to our hospital for right upper abdominal pain lasting for 2 months. Abdominal computed tomography revealed a large exophytic soft-tissue mass in the left liver lobe. Tumor markers were within the normal range. Octreoscan confirmed the primary hepatic origin of neuroendocrine tumor. The patient underwent left hepatic resection. Pathological and immunohistochemical examination of the resected specimen showed a well-differentiated grade 2 neuroendocrine tumor. Clinical discussion: Primary hepatic neuroendocrine tumors represent rare hepatic tumors. These tumors may occur at any age with an average of 50 years. Diagnosis algorithm includes two key steps: firstly, the confirmation of the endocrine nature of the tumor and secondly the confirmation of its primary nature. Conclusion: Neuroendocrine tumors are a very rare entity. The primary hepatic location is exceptional. The diagnosis is based on pathological and immunohistochemical examination as well as the result of the octreoscan.

Littoral Cell Angioma of Spleen: A rare case report.

Introduction: Spleen's Littoral Cell Angioma is a rare benign vascular tumor. The main clinical presentation is isolated splenomegaly. Case presentation: we present the case of a 37 years old male patient who suffers from chronic pain in the left hypochondrium.The abdominal examination finds a painful splenomegaly related to a biological bicytopenia. The CT Scan shows a 32 cm splenomegaly.An exploratory laparotomy with splenectomy was performed. The histological and immunohistochemical study confirmed The final diagnosis of Littoral Cell Angioma. Clinical discussion: Isolated splenomegaly of unknown etiology is the main clinical sign. Splenectomy is required for a diagnostic purpose and substratum for histological study. Conclusion: Littoral Cell Angioma of the Spleen is a rare benign vascular tumor, however it should be highlighted by clinical and radiological features, the definitive diagnosis is made upon histological study.

Mesenteric cystic lymphangioma in an adult: An unusual case report.

Introduction: Cystic lymphangioma is a benign malformation tumor of the lymphatic system. Its location is variable, and mesenteric localization remains extremely rare. Case presentation: We describe a rare case of cystic lymphangioma of the mesentery in a 26 years old woman. The diagnosis was suspected following an abdominopelvic computed tomography (CT) and magnetic resonance imaging (MRI), showing a large polylobulated cyst in contact with the stomach, the tail of the pancreas, the spleen, and the antero-external cortex of the left kidney. The patient underwent laparoscopic surgery with a pericystectomy. Pathological examination confirmed the diagnosis of cystic lymphangioma of the mesentery. The patient's postoperative recovery was uneventful. After a Follow up of one year after surgery, there was no evidence of recurrence. Clinical discussion: Cystic lymphangioma of the mesentery is a benign malformation tumor of the lymphatic system. Its clinical aspects are very polymorphic; the diagnosis is evoked by radiological imaging but requires pathological confirmation. Surgery is the gold standard in the management of this pathology. Conclusion: We highlight the importance of radical surgical resection to avoid Cystic lymphangioma complications and minimize the recurrence risk.

Primary peritoneal high-grade serous carcinoma in a man: A case report.

Introduction and importance: Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported in the medical literature, it's diagnosis is difficult before surgery. Case presentation: In this article, we describe the case of a patient who presented a high-grade primary peritoneal carcinoma, the diagnosis was suspected radiologically following an abdominopelvic computed tomography (CT).the patient underwent exploratory laparoscopic surgery with biopsy of several peritoneal nodules. Pathologic analysis of specimen confirmed the diagnosis of Primary peritoneal serous carcinomas. The patient died one month after his diagnosis while undergoing chemotherapy and palliative care. Clinical discussion: PPSC is an inoperable malignancy, histology staining confirms the diagnosis, the chemotherapy and palliative care are the only offered treatment. The evolution of the disease is very dark with a poor prognosis. Conclusion: We highlight the important of testicular examination to predict apparition of PPSC in the future.

Management of a Left Lateral Aortic Paraganglioma During Pregnancy: A Rare Case Report.

Paragangliomas are rare neuroendocrine tumors mostly diagnosed in young adults. Their association with pregnancy is even rarer, and their impact is even more serious in the absence of adequate management, which may vitally involve maternal and fetal prognosis. In this report, we present a rare case of a left lateral aortic paraganglioma in a pregnant woman in her third trimester during her 31 weeks of gestation, who consulted for a hypertensive peak; the methoxylated derivatives were positive. An abdominal MRI showed a left lateral aortic mass, suggesting a paraganglioma. After a multidisciplinary discussion, the patient underwent laparoscopic surgical resection of the mass after preoperative medical preparation. Pathological examination confirmed the diagnosis of paraganglioma. The overall stay was six days without any short-term complications, including anything related to fetal viability, with a vaginal delivery at 37 weeks of amenorrhea. The patient was followed up for six months with no complications. We highlight the importance of preoperative medical preparation followed by surgical resection in the framework of a multidisciplinary consultation for an improved maternal-fetal prognosis.

Desmoid tumor of the anterolateral abdominal wall: A rare case report.

INTRODUCTION AND IMPORTANCE: Desmoid tumors of the abdominal wall are rare fibroblastic proliferative tissue, included in the group of soft tissue tumors, not metastasizing but locally aggressive as an infiltrating tumor and a source of recurrence. CASE PRESENTATION: This case report describes a rare case of desmoid tumor of the anterolateral abdominal wall presented with a large mass of the left flank and iliac fossa. The diagnostic was suspected radiologically following an abdominopelvic computed tomography (CT) and magnetic resonance imaging (MRI). An exploratory laparotomy found a large mass infiltrating the left rectus abdominis muscle, a part of the flat left abdominal muscles, and the left iliac crest. The patient underwent a total resection of the mass involving the left rectus muscle with autoplasty by a pedicled flap of the left LATA fascia with the placement of a bifacial mesh.Histologic analysis of the operatory specimen confirmed the diagnosis of a desmoid tumor of the abdominal wall.The patient has been discharged from the hospital on the fifth day post-operatory with an uneventful recovery; she was in good health after a one-year follow-up. CLINICAL DISCUSSION: Desmoid tumors of the abdomen are very rare. Although this tumor is histologically benign, it has the potential of invading vital structures and has a high rate of local recurrence.Histology staining confirms the diagnosis, surgery is the gold standard in the management of this pathology. CONCLUSION: We highlight the importance of radical surgical excision to avoid desmoid tumor complications and to minimize the recurrence risk.

Giant parathyroid carcinoma: Diagnostic, difficulties and therapeutic strategies: A case report.

INTRODUCTION: Parathyroid carcinoma is a very aggressive malignant tumor. It is mostly revealed by clinical primary hyperparathyroidism. CASE PRESENTATION: We report a rare case of parathyroid carcinoma in a 61-year-old-male patient who presented with a painless right-sided cervical tumefaction of hard consistency associated with cervical lymphadenopathy. Cervical ultrasonography showed a right parathyroid mass with intimate contact with the homolateral thyroid lobe. A parathyroidectomy enlarged to the adjacent thyroid parenchyma with a selective neck dissection level VI was performed. CLINICAL DISCUSSION: The clinical presentation is most often manifested with clinical features of primary hyperparathyroidism associating bone disorders. Surgery remains the treatment of choice. The benefit of adjuvant treatments is controversial and remains to be evaluated. CONCLUSION: Parathyroid carcinoma is a rare tumor. This rare entity is often presented with clinicobiological features of severe primary hyperparathyroidism.

[Intussusception due to Meckel´s diverticulum in adults: a case report]. / Invagination intestinale sur diverticule de Meckel chez l´adulte: à propos d´un cas.

Meckel´s diverticulum is the most common congenital anomaly affecting the gastrointestinal tract resulting from failure of involution of the omphalomesenteric duct. This anomaly is most often asymptomatic and may be revealed by a complication, such as intussusception. This study reports the diagnostic pathway and the management of an 18-year-old female patient admitted to the Emergency Department with ileoileal invagination due to Meckel´s diverticulum complicated by occlusion. This study is interesting because it provides an overview of this rare disease whose diagnosis, based on abdominal scanner, must be made early in order to prevent small bowel perforation or necrosis. Bowel resection without desinvagination is the gold standard treatment.