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1.
Med Gas Res ; 10(1): 27-29, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32189666

RESUMO

In intensive care medicine heat moisture exchangers are standard tools to warm and humidify ventilation gases in order to prevent temperature loss of patients or airway epithelia damage. Despite being at risk of hypothermia especially after trauma, intubated emergency medicine patients are often ventilated with dry and in winter probably cold ventilation gases. We tried to assess the amount of temperature-loss due to ventilation with cold, dry medical oxygen in comparison to ventilation with warm and humidified oxygen. We ventilated a 50-kg water-dummy representing the calorimetric capacity of a 60-kg patient over a period of 2 hours (tidal volume 6.6 mL/kg = 400 mL; respiratory rate 13/min). Our formal null-hypothesis was that there would be no differences in temperature loss in a 50 kg water-dummy between ventilation with dry oxygen at 10°C vs. ventilation with humidified oxygen at 43°C. After 2 hours the temperature in the water-dummy using cold and dry oxygen was 29.7 ± 0.1°C compared to 30.4 ± 0.1°C using warm and humidified oxygen. This difference in cooling rates between both ventilation attempts of 0.7 ± 0.1°C after 2 hours represents an increased cooling rate of ~0.35°C per hour. Ventilation with cool, dry oxygen using an automated transport ventilator resulted in a 0.35°C faster cooling rate per hour than ventilation with warm humidified oxygen in a bench model simulating calorimetric features of a 60-kg human body.


Assuntos
Calorimetria , Modelos Teóricos , Respiração Artificial , Temperatura
3.
Resuscitation ; 64(3): 321-5, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15733761

RESUMO

During CPR, an inspiratory time of 2 s is recommended when the airway is unprotected; indicating that approximately 30% of the resuscitation attempt is spent on ventilation, but not on chest compressions. Since survival rates may not decrease when ventilation levels are relatively low, and uninterrupted chest compressions with a constant rate of approximately 100/min have been shown to be lifesaving, it may be beneficial to cut down the time spent on ventilation, and instead, increase the time for chest compressions. In an established bench model of a simulated unprotected airway, we evaluated if inspiratory time can be decreased from 2 to 1 s at different lower oesophageal sphincter pressure (LOSP) levels during ventilation with a bag-valve-mask device. In comparison with an inspiratory time of 2 s, 1 s resulted in significantly (p < 0.001) higher peak airway pressure and peak inspiratory flow rate, while lung tidal volumes at all LOSP levels were clinically comparable. Neither ventilation strategy produced stomach inflation at 20 cmH2O LOSP, and 1 s versus 2 s inspiratory time did not produce significantly higher (mean +/- S.D.) stomach inflation at 15 (8 +/-9 ml versus 0 +/- 0 ml; p < 0.01) and 10 cmH2O LOSP (69 +/- 20 ml versus 34 +/- 18 ml; p < 0.001), and significantly lower stomach inflation at 5 cmH2O LOSP (219 +/- 16 ml versus 308 +/- 21 ml; p < 0.001) per breath. Total cumulative stomach inflation volume over constantly decreasing LOSP levels with an inspiratory time of 2 s versus 1 s was higher (6820 ml versus 5920 ml). In conclusion, in this model of a simulated unprotected airway, a reduction of inspiratory time from 2 to 1 s resulted in a significant increase of peak airway pressure and peak inspiratory flow rate, while lung tidal volumes remained clinically comparable (up to approximately 15% difference), but statistically different due to the precise measurements. Theoretically, this may increase the time available for, and consequently the actual number of, chest compressions during CPR by approximately 25% without risking an excessive increase in stomach inflation.


Assuntos
Reanimação Cardiopulmonar/métodos , Respiração Artificial , Mecânica Respiratória , Resistência das Vias Respiratórias , Benchmarking , Esfíncter Esofágico Inferior/fisiologia , Humanos , Medidas de Volume Pulmonar , Modelos Biológicos , Estômago/fisiologia , Volume de Ventilação Pulmonar , Fatores de Tempo , Ventiladores Mecânicos
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