RESUMO
Survivors of periventricular or intraventricular hemorrhage and isolated ventricular dilation showed a higher incidence of major developmental problems in the motor areas than matched control subjects in infancy. This effect is still seen, but less evident in early childhood. Problems were mainly related to grades III and IV periventricular or intraventricular hemorrhage and isolated ventricular dilation. The outcome of newborns with grades I and II hemorrhage was benign.
Assuntos
Hemorragia Cerebral/epidemiologia , Ventrículos Cerebrais , Hemorragia Cerebral/complicações , Ventrículos Cerebrais/patologia , Desenvolvimento Infantil , Deficiências do Desenvolvimento/diagnóstico , Deficiências do Desenvolvimento/epidemiologia , Deficiências do Desenvolvimento/etiologia , Dilatação Patológica/complicações , Dilatação Patológica/epidemiologia , Seguimentos , Humanos , Recém-Nascido de Baixo Peso , Recém-Nascido , Exame Neurológico , Doenças Neuromusculares/diagnóstico , Doenças Neuromusculares/epidemiologia , Doenças Neuromusculares/etiologia , Probabilidade , Testes Psicológicos , UltrassonografiaRESUMO
Twenty-five children whose mothers had been given ethanol for the arrest of preterm labor were evaluated at 4 to 7 years of age and compared with matched control subjects. The group as a whole showed no major differences from control subjects. However, when a subgroup of children born during or within 15 hours of termination of the infusion was investigated, significant pathology in developmental and personality evaluations were noted. It is concluded that if ethanol infusion is to be used, the patient should be carefully evaluated during the infusion. If it appears that labor is progressing, the infusion should be discontinued so as to allow a maximal drug-free interval before delivery.