[Zinc and its status in some dermatologic diseases--a statistical assessment]. / Zink und sein Stellenwert bei einigen dermatologischen Erkrankungen--eine statistische Auswertung.

This report contains statistical interpretations of blood- and serum-levels of zinc, magnesium and copper, including dates of 380 patients with alopecia areata, alopecia androgenetica, psoriasis vulgaris, vitiligo, rosacea, venous ulcer and atopic eczema, compared with 31 healthy people. Significant low blood-levels of zinc were only proved in vitiligo, significant high levels were found in all patients of the psoriasis group. The serum-level of zinc was low in diagnoses as well as the blood-levels of copper. Blood- and serum-levels of magnesium were similar in all dermatological diseases; all of them were increased in comparison with the control group (significance level p = 0.05). Furthermore there were linear dependences of the variables, due to the examined diseases. It is of some interest that we could not prove a normal distribution of blood- and serum-levels of magnesium as often described in literature.

Leukapheresis in the treatment of cutaneous T-cell lymphomas.

In six patients with cutaneous T-cell lymphomas (CTCL), the effect of leukapheresis (LPH) on the disease and on various immunological and haematological parameters was investigated. Enriched mononuclear cells were removed by continuous centrifugation leukapheresis from the peripheral blood of the patients. A profound and longlasting effect was seen in one patient with the Sézary variant; a moderate response was seen in two other Sézary patients. No benefit was observed in two patients with more aggressive leukaemic disease, and one patient with plaque stage MF responded on two occasions. No limiting side effects were recognized and no consistent changes of immunological or haematological parameters were observed after LPH.